Evidence map›Paper›PMID 31213554›Full record

ArticlemBio2019

Identification of Pneumococcal Factors Affecting Pneumococcal Shedding Shows that the

M Ammar Zafar, Alexandria J Hammond, Shigeto Hamaguchi, Weisheng Wu, Masamitsu Kono, Lili Zhao, Jeffrey N Weiser

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Influenza A Virus Coinfection AltersbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Mechanisms of bacterial host-to-host transmission.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  5. Article
  6. Review
  7. Biological puzzles solved by usingJournal of bacteriology · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. d-Alanylation of Lipoteichoic Acids inFrontiers in microbiology · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. An in vivo atlas of host-pathogen transcriptomes duringProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

M Ammar ZafarDepartment of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.ORCID 0000-0002-3737-0422
Alexandria J HammondDepartment of Microbiology, New York University, New York, New York, USA.
Shigeto HamaguchiDivision of Infection Control and Prevention, Osaka University Hospital, Osaka, Japan.
Weisheng WuBRCF Bioinformatics Core, University of Michigan, Ann Arbor, Michigan, USA.
Masamitsu KonoDepartment of Otolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.
Lili ZhaoDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.
Jeffrey N WeiserDepartment of Microbiology, New York University, New York, New York, USA jeffrey.weiser@nyumc.org.ORCID 0000-0001-7168-8090
New York University · USUniversity of Michigan · USOsaka University Hospital · JPWakayama Medical University · JPWake Forest University · US

Funding

ROLE OF OPACITY VARIATION IN PNEUMOCOCCAL PATHOGENESISR01AI038446 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI WEISER, JEFFREY NEAL · 1996 to 2019
$7.4M
Mechanisms of Pneumococcal Persistence During CarriageR37AI038446 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Jeffrey Neal Weiser · 2020 to 2026
$3.8M
Early Events in Pneumococcal ColonizationR01AI105168 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI WEISER, JEFFREY NEAL · 2014 to 2018
$2.1M
NIAID NIH HHS R01 AI038446NIAID NIH HHS R01 AI105168NIAID NIH HHS R37 AI038446
6 · The paper itself

Abstract

Host-to-host transmission is a necessary but poorly understood aspect of microbial pathogenesis. Herein, we screened a genomic library of mutants of the leading respiratory pathogen

Indexed as

Bacterial SheddingInflammationAlanineAnimalsAnimals, NewbornBacterial ProteinsDisease Models, AnimalDNA Transposable ElementsGenomic LibraryHost-Pathogen InteractionsLipopolysaccharidesMiceMice, Inbred C57BLMutagenesisPneumococcal InfectionsRespiratory SystemAlanineBacterial ProteinsDNA Transposable ElementsLipopolysaccharideslipoteichoic acidTeichoic Acidsbacterial transmissionhost-pathogen interactionsinflammationStreptococcus pneumoniaetransposon mutagenesis

Identifiers

PMID31213554
PMCPMC6581856
OpenAlexW2953173473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.