Evidence map›Paper›PMID 31213470›Full record

ArticleDiabetes care2019

A Genome-Wide Association Study Identifies Blood Disorder-Related Variants Influencing Hemoglobin A

Jee-Young Moon, Tin L Louie, Deepti Jain, Tamar Sofer, Claudia Schurmann, Jennifer E Below, Chao-Qiang Lai, M Larissa Aviles-Santa, Gregory A Talavera, Caren E Smith and 15 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review of methods for detecting glycemic disorders.Diabetes research and clinical practice · 2020
    Review
  10. Association ofBMJ open diabetes research & care · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 13 institutions in 2 countries.

Jee-Young MoonDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.ORCID 0000-0001-9218-8335
Tin L LouieDepartment of Biostatistics, University of Washington, Seattle, WA.
Deepti JainDepartment of Biostatistics, University of Washington, Seattle, WA.
Tamar SoferDepartment of Biostatistics, University of Washington, Seattle, WA.
Claudia SchurmannThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Jennifer E BelowHuman Genetics Center, University of Texas Health Science Center at Houston, Houston, TX.
Chao-Qiang LaiJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA.
M Larissa Aviles-SantaNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Gregory A TalaveraGraduate School of Public Health, San Diego State University, San Diego, CA.
Caren E SmithJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA.
Lauren E PettyHuman Genetics Center, University of Texas Health Science Center at Houston, Houston, TX.
Erwin P BottingerDepartment of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Yii-Der Ida ChenInstitute for Translational Genomics and Population Sciences, Harbor-UCLA Medical Center, Torrance, CA.
Kent D TaylorInstitute for Translational Genomics and Population Sciences, Harbor-UCLA Medical Center, Torrance, CA.
Martha L DaviglusInstitute for Minority Health Research, University of Illinois at Chicago, Chicago, IL.
Jianwen CaiDepartment of Biostatistics and Collaborative Studies Coordinating Center, University of North Carolina, Chapel Hill, NC.
Tao WangDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.
Katherine L TuckerDepartment of Biomedical and Nutritional Sciences, University of Massachusetts Lowell, Lowell, MA.
José M OrdovásJean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA.
Craig L HanisHuman Genetics Center, University of Texas Health Science Center at Houston, Houston, TX.ORCID 0000-0002-4880-5348
Ruth J F LoosThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Neil SchneidermanDepartment of Psychology, University of Miami, Miami, FL.
Jerome I RotterInstitute for Translational Genomics and Population Sciences, Harbor-UCLA Medical Center, Torrance, CA.
Robert C KaplanDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.
Qibin QiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY qibin.qi@einstein.yu.edu.ORCID 0000-0002-2687-1758
Albert Einstein College of Medicine · USIcahn School of Medicine at Mount Sinai · USThe University of Texas Health Science Center at Houston · USUCLA Medical Center · USTufts University · USUniversity of Washington · USBrigham and Women's Hospital · USMadrid Institute for Advanced Studies · ESNational Institutes of Health · USSan Diego State University · USUniversity of Illinois Chicago · USUniversity of Massachusetts Lowell · USUniversity of Miami · US

Funding

Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrea L Hevener · 2003 to 2026
$40.4M
TRANSGENIC COREP60DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI BELL, GRAEME I · 1985 to 2012
$25.5M
Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI GRAEME I BELL, Raghavendra G Mirmira · 2013 to 2026
$20.9M
Clinical and Translational Science Coordinating CenterU54TR000123 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2017
$14.2M
STATISTICSP50HL105185 · NHLBI · UNIVERSITY OF MASSACHUSETTS LOWELL · PI ORDOVAS, JOSE M. · 2010 to 2015
$10.4M
Center for Research/Nutrition &Health among the ElderlyP01AG023394 · NIA · TUFTS UNIVERSITY BOSTON · PI TUCKER, KATHERINE L · 2003 to 2007
$8.1M
DIETARY PATTERNS AND RISK OF CARDIOVASCULAR DISEASER01HL060712 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI HU, FRANK B, QI, QIBIN · 1998 to 2021
$8.0M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Ultra-processed Foods, Diet Quality, and Cardiometabolic Health: An Inter-disciplinary Trans-Atlantic Collaborative ProjectR01DK120870 · NIDDK · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Qibin Qi, Qi Sun · 2019 to 2026
$4.2M
Integrated analysis of CVD risk in HIV: gut microbiota, immune function and metabolitesR01HL140976 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KAPLAN, ROBERT C, KNIGHT, ROB · 2018 to 2021
$3.3M
GWAS for Sleep Apnea and Endothelial Function Among Mexican AmericansR01HL102830 · NHLBI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HANIS, CRAIG L · 2010 to 2013
$2.8M
Identification and Replication of Type 2 Diabetes Genes in Mexican AmericansU01DK085501 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HANIS, CRAIG L · 2009 to 2013
$2.7M
NCATS NIH HHS U54 TR000123NHGRI NIH HHS HHSN268200782096CNHLBI NIH HHS HHSN268201300005CNHLBI NIH HHS K01 HL129892NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS P50 HL105185NHLBI NIH HHS R01 HL060712NHLBI NIH HHS R01 HL102830NHLBI NIH HHS R01 HL140976NIAID NIH HHS R01 AI085014NIA NIH HHS P01 AG023394NIDDK NIH HHS P30 DK020595NIDDK NIH HHS P30 DK063491NIDDK NIH HHS P30 DK111022NIDDK NIH HHS P60 DK020595NIDDK NIH HHS R01 DK073541NIDDK NIH HHS R01 DK119268NIDDK NIH HHS R01 DK120870NIDDK NIH HHS U01 DK085501
6 · The paper itself

Abstract

objectiveWe aimed to identify hemoglobin A RESEARCH DESIGN AND

methodsWe conducted a genome-wide association study (GWAS) of HbA

resultsOur GWAS and replication analyses showed 10 previously known and novel loci associated with HbA

conclusionsThis study in U.S. Hispanics/Latinos found several ancestry-specific alleles associated with HbA

Indexed as

AdultAllelesBlood GlucoseDiabetes MellitusFastingFemaleGenetic VariationGenome-Wide Association StudyGlucose Tolerance TestGlycated HemoglobinHematologic DiseasesHispanic or LatinoHumansHyperglycemiaMaleMiddle AgedBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID31213470
PMCPMC6702612
OpenAlexW2952539431

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.