Evidence map›Paper›PMID 31212861›Full record

ArticleCancers2019

Aberrant MicroRNA Expression and Its Implications for Uveal Melanoma Metastasis.

Kyra N Smit, Jiang Chang, Kasper Derks, Jolanda Vaarwater, Tom Brands, Rob M Verdijk, Erik A C Wiemer, Hanneke W Mensink, Joris Pothof, Annelies de Klein and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Role of miRNA in adult ocular tumorigenesis.Frontiers in molecular biosciences · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Cancers · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Emerging roles of microRNAs and their implications in uveal melanoma.Cellular and molecular life sciences : CMLS · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kyra N SmitDepartment of Ophthalmology, Erasmus University MC, 3015 GD Rotterdam, The Netherlands. k.n.smit@erasmusmc.nl.
Jiang ChangDepartment of Molecular Genetics, Erasmus University MC, 3015 GD Rotterdam, The Netherlands. j.chang@erasmusmc.nl.
Kasper DerksDepartment of Molecular Genetics, Erasmus University MC, 3015 GD Rotterdam, The Netherlands. kasper.derks@mumc.nl.
Jolanda VaarwaterDepartment of Ophthalmology, Erasmus University MC, 3015 GD Rotterdam, The Netherlands. j.vaarwater@erasmusmc.nl.
Tom BrandsDepartment of Clinical Genetics, Erasmus University MC, 3015 GD Rotterdam, The Netherlands. t.brands@erasmusmc.nl.ORCID 0000-0003-0865-8934
Rob M VerdijkDepartment of Pathology, Section Ophthalmic Pathology, Erasmus University MC, 3015 GD Rotterdam, The Netherlands. r.verdijk@erasmusmc.nl.ORCID 0000-0003-1437-214X
Erik A C WiemerDepartment of Medical Oncology, Erasmus University MC, 3015 GD Rotterdam, The Netherlands. e.wiemer@erasmusmc.nl.ORCID 0000-0002-0673-7236
Hanneke W MensinkThe Rotterdam Eye Hospital, 3011 BH Rotterdam, The Netherlands. h.mensink@oogziekenhuis.nl.
Joris PothofDepartment of Molecular Genetics, Erasmus University MC, 3015 GD Rotterdam, The Netherlands. j.pothof@erasmusmc.nl.
Annelies de KleinDepartment of Clinical Genetics, Erasmus University MC, 3015 GD Rotterdam, The Netherlands. a.deklein@erasmusmc.nl.
Emine KilicDepartment of Ophthalmology, Erasmus University MC, 3015 GD Rotterdam, The Netherlands. e.kilic@erasmusmc.nl.
Erasmus University Rotterdam · NLRotterdam Eye Hospital · NL

Funding

Stichting Combined Ophthalmic Research Rotterdam .
6 · The paper itself

Abstract

Uveal melanoma (UM) is the most frequently found primary intra-ocular tumor in adults. It is a highly aggressive cancer that causes metastasis-related mortality in up to half of the patients. Many independent studies have reported somatic genetic changes associated with high metastatic risk, such as monosomy of chromosome 3 and mutations in

Indexed as

IPA pathway analysismetastasismicroRNAsmRNA expressionuveal melanoma

Identifiers

PMID31212861
PMCPMC6628189
OpenAlexW2952466149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.