Evidence map›Paper›PMID 31212828›Full record

ArticleInternational journal of molecular sciences2019

Src and ROCK Kinases Differentially Regulate Mineralization of Human Osteosarcoma Saos-2 Cells.

Agnieszka Strzelecka-Kiliszek, Marta Romiszewska, Lukasz Bozycki, Saida Mebarek, Joanna Bandorowicz-Pikula, Rene Buchet, Slawomir Pikula

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Apigenin Modulates AnxA6- and TNAP-Mediated Osteoblast Mineralization.International journal of molecular sciences · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Agnieszka Strzelecka-KiliszekLaboratory of Biochemistry of Lipids, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Str., 02-093 Warsaw, Poland. a.strzelecka-kiliszek@nencki.gov.pl.
Marta RomiszewskaLaboratory of Biochemistry of Lipids, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Str., 02-093 Warsaw, Poland. m.romiszewska@nencki.gov.pl.
Lukasz BozyckiLaboratory of Biochemistry of Lipids, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Str., 02-093 Warsaw, Poland. l.bozycki@nencki.gov.pl.
Saida MebarekUniversité de Lyon, CEDEX 69622 Villeurbanne, France. saida.mebarek@univ-lyon1.fr.
Joanna Bandorowicz-PikulaLaboratory of Cellular Metabolism, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Str., 02-093 Warsaw, Poland. j.bandorowicz-pikula@nencki.gov.pl.
Rene BuchetUniversité de Lyon, CEDEX 69622 Villeurbanne, France. rene.buchet@univ-lyon1.fr.ORCID 0000-0002-7966-3856
Slawomir PikulaLaboratory of Biochemistry of Lipids, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Str., 02-093 Warsaw, Poland. s.pikula@nencki.gov.pl.ORCID 0000-0003-4640-3094
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego · PLUniversité Claude Bernard Lyon 1 · FR

Funding

ERA-CVD ERA-CVD/MICROEXPLORATION/4/2018Narodowe Centrum Nauki 2016/23/B/NZ3/03116POLONIUM no 1/A/1 for years 2018/2019
6 · The paper itself

Abstract

Osteoblasts initiate bone mineralization by releasing matrix vesicles (MVs) into the extracellular matrix (ECM). MVs promote the nucleation process of apatite formation from Ca

Indexed as

Calcification, PhysiologicAnnexinsBiomarkersBone NeoplasmsCell Line, TumorCell ProliferationCell SurvivalExtracellular MatrixFluorescent Antibody TechniqueHumansOsteosarcomaProto-Oncogene Masrho-Associated Kinasessrc-Family KinasesAnnexinsBiomarkersMAS1 protein, humanProto-Oncogene Masrho-Associated Kinasessrc-Family Kinasesannexin A6matrix vesiclesmineralizationROCKSaos-2 cellsSrc kinase

Identifiers

PMID31212828
PMCPMC6628028
OpenAlexW2952883244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.