Evidence map›Paper›PMID 31212825›Full record

ArticleJournal of clinical medicine2019

Occurrence of Antithrombotic Related Adverse Events in Hospitalized Patients: Incidence and Clinical Context between 2008 and 2016.

Marco J Moesker, Bernadette C F M Schutijser, Janke F de Groot, Maaike Langelaan, Peter Spreeuwenberg, Menno V Huisman, Martine C de Bruijne, Cordula Wagner

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Marco J MoeskerDepartment of Public and Occupational Health, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute, De Boelelaan 1117, 1081 BT Amsterdam, The Netherlands. m.moesker@vumc.nl.ORCID 0000-0002-3546-760X
Bernadette C F M SchutijserDepartment of Public and Occupational Health, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute, De Boelelaan 1117, 1081 BT Amsterdam, The Netherlands. b.schutijser@vumc.nl.ORCID 0000-0002-8957-4590
Janke F de GrootNetherlands Institute for Health Services Research (NIVEL), 3513 CR Utrecht, The Netherlands. j.degroot@nivel.nl.
Maaike LangelaanPinkRoccade healthcare, 7324 AE Apeldoorn, The Netherlands. Maaike.Langelaan@PinkRoccade.nl.
Peter SpreeuwenbergNetherlands Institute for Health Services Research (NIVEL), 3513 CR Utrecht, The Netherlands. p.spreeuwenberg@nivel.nl.
Menno V HuismanDepartment of Thrombosis and Hemostasis, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands. m.v.huisman@lumc.nl.ORCID 0000-0003-1423-5348
Martine C de BruijneDepartment of Public and Occupational Health, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute, De Boelelaan 1117, 1081 BT Amsterdam, The Netherlands. mc.debruyne@vumc.nl.ORCID 0000-0003-1838-1158
Cordula WagnerDepartment of Public and Occupational Health, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute, De Boelelaan 1117, 1081 BT Amsterdam, The Netherlands. c.wagner@nivel.nl.
Amsterdam University Medical Centers · NLNetherlands Institute for Health Services Research · NLLeiden University Medical Center · NL

Funding

Ministerie van Volksgezondheid, Welzijn en Sport n/a
6 · The paper itself

Abstract

Antithrombotic drugs are consistently involved in medication-related adverse events (MRAEs) in hospitalized patients. We aimed to estimate the antithrombotic-related adverse event (ARAE) incidence between 2008 and 2016 and analyse their clinical context in hospitalized patients in The Netherlands. A post-hoc analysis of three national studies, aimed at adverse event (AE) identification, was performed. Previously identified AEs were screened for antithrombotic involvement. Crude and multi-level, case-mix adjusted ARAE and MRAE incidences were calculated. Various contextual ARAE characteristics were analysed. ARAE incidence between 2008 and 2016 decreased significantly in in-hospital deceased patients from 1.20% (95% confidence interval (CI): 0.63-2.27%) in 2008 to 0.54% (95% CI: 0.27-1.11%) in 2015/2016 (

Indexed as

anticoagulantsantithrombotic drugsepidemiological studiesmedication safety

Identifiers

PMID31212825
PMCPMC6617527
OpenAlexW2951280794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.