Evidence map›Paper›PMID 31212768›Full record

ArticleSensors (Basel, Switzerland)2019

Hybrid Analytical Platform Based on Field-Asymmetric Ion Mobility Spectrometry, Infrared Sensing, and Luminescence-Based Oxygen Sensing for Exhaled Breath Analysis.

L Tamina Hagemann, Stefan Repp, Boris Mizaikoff

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

L Tamina HagemannInstitute of Analytical and Bioanalytical Chemistry (IABC), Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany. tamina.hagemann@uni-ulm.de.
Stefan ReppInstitute of Analytical and Bioanalytical Chemistry (IABC), Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany. stefan.repp@uni-ulm.de.
Boris MizaikoffInstitute of Analytical and Bioanalytical Chemistry (IABC), Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany. boris.mizaikoff@uni-ulm.de.
Universität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The reliable online analysis of volatile compounds in exhaled breath remains a challenge, as a plethora of molecules occur in different concentration ranges (i.e., ppt to %) and need to be detected against an extremely complex background matrix. Although this complexity is commonly addressed by hyphenating a specific analytical technique with appropriate preconcentration and/or preseparation strategies prior to detection, we herein propose the combination of three different detector types based on truly orthogonal measurement principles as an alternative solution: Field-asymmetric ion mobility spectrometry (FAIMS), Fourier-transform infrared (FTIR) spectroscopy-based sensors utilizing substrate-integrated hollow waveguides (iHWG), and luminescence sensing (LS). By carefully aligning the experimental needs and measurement protocols of all three methods, they were successfully integrated into a single compact analytical platform suitable for online measurements. The analytical performance of this prototype system was tested via artificial breath samples containing nitrogen (N

Indexed as

Biosensing TechniquesBreath TestsExhalationHumansIon Mobility SpectrometryLuminescenceOxygenVolatile Organic CompoundsOxygenVolatile Organic Compoundsacetonecarbon dioxideexhaled breath analysisfield-asymmetric ion mobility spectrometry (FAIMS)Fourier-transform infrared spectroscopy (FTIR)hybrid techniqueshyphenated techniquesinfrared sensorsluminescence sensingoxygen

Identifiers

PMID31212768
PMCPMC6630267
OpenAlexW2949116921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.