Evidence map›Paper›PMID 31212762›Full record

ArticleInternational journal of molecular sciences2019

A Profile of the In Vitro Anti-Tumor Activity and In Silico ADME Predictions of Novel Benzothiazole Amide-Functionalized Imidazolium Ionic Liquids.

Fawzia Al-Blewi, Nadjet Rezki, Arshi Naqvi, Husna Qutb Uddin, Salsabeel Al-Sodies, Mouslim Messali, Mohamed Reda Aouad, Sanaa Bardaweel

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Click synthesis of some novel benzo[RSC medicinal chemistry · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. ACS omega · 2021
    Article
  9. Article
  10. Review
  11. Ionic Liquids Toxicity-Benefits and Threats.International journal of molecular sciences · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fawzia Al-BlewiDepartment of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia. ffs.chem334@gmail.com.
Nadjet RezkiDepartment of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia. nadjetrezki@yahoo.fr.ORCID 0000-0001-8330-1738
Arshi NaqviDepartment of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia. arshi_84@yahoo.com.ORCID 0000-0002-9211-7139
Husna Qutb UddinDepartment of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia. mo-019-you@hotmail.com.
Salsabeel Al-SodiesDepartment of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia. s7l_88@hotmail.com.
Mouslim MessaliDepartment of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia. aboutasnim@yahoo.fr.
Mohamed Reda AouadDepartment of Chemistry, Faculty of Science, Taibah University, Al-Madinah Al-Munawarah 30002, Saudi Arabia. aouadmohamedreda@yahoo.fr.ORCID 0000-0001-7018-6654
Sanaa BardaweelDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Jordan, Amman 11942, Jordan. S.Bardaweel@ju.edu.jo.ORCID 0000-0002-4823-0708

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A focused array of green imidazolium ionic liquids (ILs) encompassing benzothiazole ring and amide linkage were designed and synthesized using quaternization and metathesis protocols. The synthesized ILs have been fully characterized by usual spectroscopic methods and screened for their anticancer activities against human cancer cell lines originating from breast and colon cancers. Collectively, our biological data demonstrate that the newly synthesized series has variable anticancer activities in the examined cancer types. The synthesized ILs

Indexed as

Antineoplastic AgentsApoptosisBenzothiazolesCell Line, TumorCell ProliferationChemical PhenomenaHumansImidazolesIonic LiquidsMagnetic Resonance SpectroscopyAntineoplastic AgentsBenzothiazolesImidazolesIonic LiquidsADMEanticancerbenzothiazoleimidazoleionic liquids

Identifiers

PMID31212762
PMCPMC6627815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.