Evidence map›Paper›PMID 31212754›Full record

ReviewMicromachines2019

Microfluidic Technology for Clinical Applications of Exosomes.

Florina S Iliescu, Danilo Vrtačnik, Pavel Neuzil, Ciprian Iliescu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Micromachines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  19. Liquid Biopsy: A Game Changer for Type 2 Diabetes.International journal of molecular sciences · 2024
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Florina S IliescuSchool of Applied Science, Republic Polytechnic Singapore, Singapore 738964, Singapore. florina_iliescu@rp.edu.sg.
Danilo VrtačnikLaboratory of Microsensor Structures and Electronics, Faculty of Electrical Engineering, University of Ljubljana, SI-1000 Ljubljana, Slovenia. danilo.vrtacnik@fe.uni-lj.si.
Pavel NeuzilMinistry of Education Key Laboratory of Micro/Nano Systems for Aerospace, School of Mechanical Engineering, Northwestern Polytechnical University, Xi'an 710072, China. pavel.neuzil@nwpu.edu.cn.ORCID 0000-0001-9040-281X
Ciprian IliescuBiomedical Institute for Global Health Research and Technology (BIGHEART), National University of Singapore, Singapore 117599, Singapore. cipi_sil@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes, a type of nanovesicle, are distinct cellular entities specifically capable of carrying various cargos between cells. It has been hypothesized that exosomes, as an enriched source of biomolecules, may serve as biomarkers for various diseases. This review introduces general aspects of exosomes, presents the challenges in exosome research, discusses the potential of exosomes as biomarkers, and describes the contribution of microfluidic technology to enable their isolation and analysis for diagnostic and disease monitoring. Additionally, clinical applications of exosomes for diagnostic purposes are also summarized.

Indexed as

cancerclinical applicationsexosomesextracellular vesiclesinflammationmicrofluidics

Identifiers

PMID31212754
PMCPMC6631586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.