Evidence map›Paper›PMID 31212689›Full record

ArticleMolecules (Basel, Switzerland)2019

In Vitro Human Metabolism and Inhibition Potency of Verbascoside for CYP Enzymes.

Anna-Mari Reid, Risto Juvonen, Pasi Huuskonen, Marko Lehtonen, Markku Pasanen, Namrita Lall

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Verbascoside-richFrontiers in bioengineering and biotechnology · 2026
    Article
  2. Review
  3. The In Vitro Pharmacokinetics of Medicinal Plants: A Review.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Verbascoside-Rich Plant Extracts in Animal Nutrition.Antioxidants (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Photoprotective Activity ofPlants (Basel, Switzerland) · 2021
    Article
  10. Formulation of a Phenol-Rich Extract from Unripe Olives (Molecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Anna-Mari ReidDepartment of Plant and Soil Sciences, University of Pretoria, Pretoria 0002, South Africa. annamarikok@gmail.com.
Risto JuvonenSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio FI-70210, Finland. risto.juvonen@uef.fi.
Pasi HuuskonenSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio FI-70210, Finland. pasi.huuskonen@uef.fi.ORCID 0000-0002-5768-4330
Marko LehtonenLC-MS Metabolomics Center, Biocentre, Kuopio, Kuopio FI-70210, Finland. marko.lehtonen@uef.fi.
Markku PasanenSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio FI-70210, Finland. markku.pasanen@uef.fi.
Namrita LallDepartment of Plant and Soil Sciences, University of Pretoria, Pretoria 0002, South Africa. namrita.lall@up.ac.za.ORCID 0000-0002-3242-3476
University of Eastern Finland · FIJSS Academy of Higher Education and Research · INUniversity of Pretoria · ZA

Funding

National Research Foundation 105169, 98334
6 · The paper itself

Abstract

Verbascoside is found in many medicinal plant families such as Verbenaceae. Important biological activities have been ascribed to verbascoside. Investigated in this study is the potential of verbascoside as an adjuvant during tuberculosis treatment. The present study reports on the in vitro metabolism in human hepatic microsomes and cytosol incubations as well as the presence and quantity of verbascoside within

Indexed as

AntioxidantsBiphenyl CompoundsCell ProliferationChromatography, High Pressure LiquidCytochrome P-450 Enzyme SystemEnzyme ActivationGlucosidesHep G2 CellsHumansNitric OxideOxidation-ReductionPhenolsPhytochemicalsPicratesPolyphenolsSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization1,1-diphenyl-2-picrylhydrazylacteosideAntioxidantsBiphenyl CompoundsCytochrome P-450 Enzyme SystemGlucosidesNitric OxidePhenolsPhytochemicalsPicratesPolyphenolsantioxidantcytochrome P450cytotoxicitylivermetabolismverbascoside

Identifiers

PMID31212689
PMCPMC6600574
OpenAlexW2950076673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.