Evidence map›Paper›PMID 31212645›Full record

ReviewInternational journal of molecular sciences2019

Frailty, Cognitive Decline, Neurodegenerative Diseases and Nutrition Interventions.

María Elena Gómez-Gómez, Sara C Zapico

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 6 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 6 syntheses or guidelines pooled it, 179 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Circulating Mediators of Apoptosis and Inflammation in Aging; Physical Exercise Intervention.International journal of environmental research and public health · 2021
    Trial
  8. Investigating Disordered Eating Behaviours Among Individuals Living With Neurodegenerative Disease: A Scoping Review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
    Article
  9. Review
  10. Article
  11. The enigma of vascular dementia: current state and emerging perspectives.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  12. Observational
  13. Article
  14. Adaptive behavior in older adults according to age and schooling.European journal of translational myology · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

María Elena Gómez-GómezCENAC Clinical Analysis Laboratories, Plaza Merced, 2, 33401 Avilés, Asturias 33401, Spain. Sealen2000@hotmail.com.
Sara C ZapicoInternational Forensic Research Institute and Chemistry Department, Florida International University, 11200 SW 8 St., CP323, Miami, FL 33199, USA. scasadoz@fiu.edu.
Smithsonian Institution · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently the human population is aging faster. This leads to higher dependency rates and the transformation of health and social care to adapt to this aged population. Among the changes developed by this population is frailty. It is defined as a clinically detectable syndrome, related to the aging of multiple physiological systems, which prompts a situation of vulnerability. The etiology of frailty seems to be multifactorial and its pathophysiology is influenced by the interaction of numerous factors. Morley et al. propose four main mechanisms triggering the frailty: atherosclerosis, sarcopenia, cognitive deterioration and malnutrition, with their respective metabolic alterations. Malnutrition is associated with cognitive impairment or functional loss, but it is also known that an inadequate nutritional status predisposes to cognitive frailty. Additionally, nutritional factors that may influence vascular risk factors will potentially have an effect on dementia decline among patients with cognitive frailty. This review aims to describe the nutritional factors that have been researched so far which may lead to the development of frailty, and especially cognitive decline.

Indexed as

Frail ElderlyAgedAged, 80 and overAlzheimer DiseaseCognitive DysfunctionFemaleFree RadicalsHumansMaleNeurodegenerative DiseasesFree RadicalsAlzheimer’s Diseaseantioxidantscognitive declinefrailtyfree radicalsneurodegenerative diseasesnutritionParkinson’s disease

Identifiers

PMID31212645
PMCPMC6600148
OpenAlexW2952015290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.