ArticleMetabolites2019
Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington's Disease.
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Article in Metabolites, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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24citing papers in PubMed, 1 pooled it
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gut microbiome in people living with HIV is associated with impaired thiamine and folate syntheses.Microbial pathogenesis · 2021Pooled it
- Nobiletin Modulates Transcriptomic and Metabolomic Alterations in Aβ42-Induced Primary Rat Astrocytes: Implications for Alzheimer's Disease.Molecular neurobiology · 2026Article
- Neurotoxic Effects of Acute Tributyltin Exposure in Adult Zebrafish: Behavioral Impairments and Mechanistic Insights.Metabolites · 2026Article
- Comparison of vitamin B levels in febrile children with and without febrile seizures: A prospective single-center study.Medicine · 2025Observational
- Say hello to my little friend… micronutraceuticals in neuroenergetics, neuronal health, and neurodegenerative diseases.Frontiers in neuroscience · 2025Review
- Development and validation of age- and sex-specific reference intervals for serum vitamin B5 in Henan pediatric population by LC-MS/MS.Frontiers in nutrition · 2025Article
- Brisk walking improves motor function and lower limb muscle strength in Chinese women aged 80 years and older.Scientific reports · 2024Article
- Role of metabolomic profile as a potential marker to discriminate membranous nephropathy from IgA nephropathy.International urology and nephrology · 2024Article
- Practical supplements for prevention and management of migraine attacks: a narrative review.Frontiers in nutrition · 2024Review
- Association of Probable Post-Traumatic Stress Disorder with Dietary Pattern and Gut Microbiome in a Cohort of Women.Nature. Mental health · 2023Article
- Antioxidants Prevent Iron Accumulation and Lipid Peroxidation, but Do Not Correct Autophagy Dysfunction or Mitochondrial Bioenergetics in Cellular Models of BPAN.International journal of molecular sciences · 2023Article
- Multi-regional alterations in glucose and purine metabolic pathways in the Parkinson's disease dementia brain.NPJ Parkinson's disease · 2023Article
- RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-8.Science advances · 2023Article
- Mapping the Influence of the Gut Microbiota on Small Molecules across the Microbiome Gut Brain Axis.Journal of the American Society for Mass Spectrometry · 2022Article
- Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer's Disease Consistent With Cerebral Pantothenate Deficiency.Frontiers in aging neuroscience · 2022Article
- Exploring Structural Mechanism of COVID-19 Treatment with Glutathione as a Potential Peptide Inhibitor to the Main Protease: Molecular Dynamics Simulation and MM/PBSA Free Energy Calculations Study.International journal of peptide research and therapeutics · 2022Article
- Contrasting Sodium and Potassium Perturbations in the Hippocampus Indicate Potential NaFrontiers in aging neuroscience · 2022Article
- The Role of Vitamins in Neurodegenerative Disease: An Update.Biomedicines · 2021Review
- Substantively Lowered Levels of Pantothenic Acid (Vitamin B5) in Several Regions of the Human Brain in Parkinson's Disease Dementia.Metabolites · 2021Article
- The Use of 'Omics for Diagnosing and Predicting Progression of Chronic Kidney Disease: A Scoping Review.Frontiers in genetics · 2021Article
Corrections and comments
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Authors and funding
11 authors.
Stefano PatassiniCentre for Advanced Discovery and Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester M19 9NT, UK. stefano_patas@yahoo.it.
Paul BegleyCentre for Advanced Discovery and Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester M19 9NT, UK. paul.begley59@gmail.com.
Jingshu XuCentre for Advanced Discovery and Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester M19 9NT, UK. jingshu.xu@hotmail.com.
Stephanie J ChurchCentre for Advanced Discovery and Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester M19 9NT, UK. stephanie.church@manchester.ac.uk.
Nina KureishyCentre for Advanced Discovery and Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester M19 9NT, UK. kurnina@yahoo.com.
Suzanne J ReidSchool of Biological Sciences, Faculty of Science, University of Auckland, Auckland 1142, New Zealand. s.reid@auckland.ac.nz.
Henry J WaldvogelCentre for Brain Research, Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1142, New Zealand. h.waldvogel@auckland.ac.nz.
Richard L M FaullCentre for Brain Research, Department of Anatomy and Medical Imaging, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1142, New Zealand. rlm.faull@auckland.ac.nz.ORCID 0000-0003-3385-9498
Russell G SnellSchool of Biological Sciences, Faculty of Science, University of Auckland, Auckland 1142, New Zealand. r.snell@auckland.ac.nz.
Richard D UnwinCentre for Advanced Discovery and Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester M19 9NT, UK. R.Unwin@manchester.ac.uk.ORCID 0000-0001-7955-9111
Garth J S CooperCentre for Advanced Discovery and Experimental Therapeutics, Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine & Health, The University of Manchester, Manchester M19 9NT, UK. garth.cooper@manchester.ac.uk.
Funding
Endocore Research Trust GJSCHealth Research Council of New Zealand Various Programme funding (GJSC)Lotto New Zealand Various equipment and project grants (GJSC)Manchester Biomedical Research Centre and the Greater Manchester Comprehensive Local Research Network Establishment grantMaurice and Phyllis Paykel Trust Various equipment grants (GJSC)Ministry for Business Innovation and Employment Programme funding UOAX0815 (GJSC)Neurological Foundation of New Zealand RLMF, HJWOakley Mental Health Research Foundation 3456030; 3627092; 3701339; 3703253; and 3702870 Project funding (GJSC)Tertiary Education Commission Programme funding (GJSC); Doctoral Scholarship (JX)University of Auckland PhD STudent PReSS funding (JX)University of Manchester, the CMFT, and the Northwest Regional Development Agency combined programme grant to CADET
Abstract
Huntington's disease (HD) is a neurodegenerative disorder caused by an expanded CAG repeat in exon 1 of the
Indexed as
acetylcholine biosynthesisacetyl-coenzyme Abioinformaticsbrain energy metabolismdata analyticsdata visualisationHuntington’s diseasemetabolomicsneurodegenerationvitamin B5
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.