Evidence map›Paper›PMID 31212601›Full record

ReviewInternational journal of molecular sciences2019

Programmed Cell Death-1 Receptor (PD-1)-Mediated Regulation of Innate Lymphoid Cells.

Grace Mallett, Arian Laurence, Shoba Amarnath

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Emerging Trends in Immunotherapy for Cancer.Diseases (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. T-Helper Cell Subset Response Is a Determining Factor in COVID-19 Progression.Frontiers in cellular and infection microbiology · 2021
    Observational
  15. Role of PD-L1 in Gut Mucosa Tolerance and Chronic Inflammation.International journal of molecular sciences · 2020
    Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Grace MallettInstitute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. g.mallett2@newcastle.ac.uk.
Arian LaurenceDepartment of Haematology, University College London Hospitals NHS Trust, London NW1 2BU, UK. laurence.arian@icloud.com.
Shoba AmarnathInstitute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. shoba.amarnath@newcastle.ac.uk.
Newcastle University · GBUniversity College London Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Programmed cell death-1 (PD-1) is a cell surface receptor that dampens adaptive immune responses. PD-1 is activated by the engagement of its ligands PDL-1 or PDL-2. This results in the inhibition of T cell proliferation, differentiation, cytokine secretion, and cytolytic function. Although a great deal is known about PD-1 mediated regulation of CD4

Indexed as

AnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHumansImmunity, InnateImmunotherapyLymphocytesProgrammed Cell Death 1 ReceptorProgrammed Cell Death 1 ReceptorILCPD-1PDL-1

Identifiers

PMID31212601
PMCPMC6601034
OpenAlexW2953107829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.