Evidence map›Paper›PMID 31211762›Full record

ReviewJournal of pediatric gastroenterology and nutrition2019

Gastrointestinal Polyposis in Pediatric Patients.

Suzanne P MacFarland, Kristin Zelley, Bryson W Katona, Benjamin J Wilkins, Garrett M Brodeur, Petar Mamula

Abstract readReview
In one paragraph

Review in Journal of pediatric gastroenterology and nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Review
  8. Article
  9. Evaluation of Classic, Attenuated, and Oligopolyposis of the Colon.Gastrointestinal endoscopy clinics of North America · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Suzanne P MacFarlandDivision of Oncology, Department of Pediatrics.
Kristin ZelleyDivision of Oncology, Department of Pediatrics.
Bryson W KatonaDivision of Gastroenterology, Department of Medicine.
Benjamin J WilkinsDepartment of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia.
Garrett M BrodeurDivision of Oncology, Department of Pediatrics.
Petar MamulaDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

Funding

Physician Scientist Training in Clinical OncologyK12CA076931 · NCI · UNIVERSITY OF PENNSYLVANIA · PI STEPHEN Patrick HUNGER, LYNN M. SCHUCHTER · 1997 to 2026
$16.5M
Pediatric Scholars ProgramK12HD043245 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ST. GEME, JOSEPH W. · 2003 to 2022
$7.4M
Menin/MLL promotes cell survival in the setting of EGFR inhibitionK08DK106489 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI KATONA, BRYSON WILLIAM · 2015 to 2019
$819k
Role of Cirhin/Utp4 in biliary development and diseaseK08DK099379 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI WILKINS, BENJAMIN J · 2014 to 2018
$737k
NCI NIH HHS K12 CA076931NICHD NIH HHS K12 HD043245NIDDK NIH HHS K08 DK099379NIDDK NIH HHS K08 DK106489
6 · The paper itself

Abstract

Gastrointestinal polyps are mucosal overgrowths that, if unchecked, can undergo malignant transformation. Although relatively uncommon in the pediatric age group, they can be the harbingers of multiorgan cancer risk and require close management and follow-up. Additionally, as many polyposis syndromes are inherited, appropriate genetic testing and management of relatives is vital for the health of the entire family. In this review, we discuss both common and uncommon childhood gastrointestinal polyposis syndromes in terms of clinical presentation, management, and surveillance. We also detail any additional malignancy risk and surveillance required in the pediatric age group (<21 years old). Through this review, we provide a framework for gastroenterologists to manage the multifaceted nature of pediatric polyposis syndromes.

Indexed as

Genetic Predisposition to DiseaseAdenomatous Polyposis ColiAdolescentChildGastrointestinal NeoplasmsGenetic CounselingGenetic TestingHumansPeutz-Jeghers SyndromePractice Guidelines as Topic

Identifiers

PMID31211762
PMCPMC7336255

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.