Evidence map›Paper›PMID 31211674›Full record

ArticleEmerging infectious diseases2019

Diagnosis of Chagasic Encephalitis by Sequencing of 28S rRNA Gene.

Ashrit Multani, Aabed Meer, Darvin S Smith, Malika N Kheraj, Edward D Plowey, Brian G Blackburn

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Emerging infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Chagas Disease: An Opportunistic Infection in AIDS.Current infectious disease reports · 2026
    Article
  4. Current tropical medicine reports · 2023
    Article
  5. Chagas Disease in People with HIV: A Narrative Review.Tropical medicine and infectious disease · 2021
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ashrit Multani
Aabed Meer
Darvin S Smith
Malika N Kheraj
Edward D Plowey
Brian G Blackburn

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of chagasic encephalitis diagnosed by 28S rRNA sequencing. The diagnosis of chagasic encephalitis is challenging, given the broad differential diagnosis for central nervous system lesions in immunocompromised patients and low sensitivity of traditional diagnostics. Sequencing should be part of the diagnostic armamentarium for potential chagasic encephalitis.

Indexed as

AdultChagas DiseaseHumansImage-Guided BiopsyImmunocompromised HostInfectious EncephalitisMagnetic Resonance ImagingMaleRNA, Ribosomal, 28SSequence Analysis, DNASymptom AssessmentTomography, X-Ray ComputedTreatment OutcomeTrypanocidal AgentsTrypanosoma cruziRNA, Ribosomal, 28STrypanocidal Agents28S rRNA geneChagas diseasechagasic encephalitisHIV/AIDS and other retrovirusesimmunocompromisedmeningitis/encephalitisparasitesprotozoarRNA sequencingTrypanosoma cruzi

Identifiers

PMID31211674
PMCPMC6590746
OpenAlexW2943833823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.