Evidence map›Paper›PMID 31211249›Full record

ArticleNPJ digital medicine2018

Data mining for health: staking out the ethical territory of digital phenotyping.

Nicole Martinez-Martin, Thomas R Insel, Paul Dagum, Henry T Greely, Mildred K Cho

Abstract read
In one paragraph

Article in NPJ digital medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Audio-based digital biomarkers in diagnosing and managing respiratory diseases: a systematic review and bibliometric analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  4. Trial
  5. Digital doppelgangers in psychiatry.Discover mental health · 2026
    Review
  6. Beyond RCTs-Better Research Designs and Methods for Psychosocial Efficacy Studies in Mental Health.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2026
    Review
  7. Rethinking Ethics for an Era of Trusted Computational Tools.The Psychiatric clinics of North America · 2026
    Review
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicole Martinez-MartinStanford University, Palo Alto, CA, USA.ORCID 0000-0001-9345-0462
Thomas R InselMindstrong Health, 248 Homer Street, Palo Alto, CA 94301, USA.
Paul DagumMindstrong Health, 248 Homer Street, Palo Alto, CA 94301, USA.
Henry T GreelyStanford University, Palo Alto, CA, USA.
Mildred K ChoStanford University, Palo Alto, CA, USA.

Funding

The Stanford Training Program in ELSI ResearchT32HG008953 · NHGRI · STANFORD UNIVERSITY · PI Mildred K. Cho, Meghan Halley · 2016 to 2026
$3.1M
NHGRI NIH HHS T32 HG008953
6 · The paper itself

Abstract

Digital phenotyping uses smartphone and wearable signals to measure cognition, mood, and behavior. This promising new approach has been developed as an objective, passive assessment tool for the diagnosis and treatment of mental illness. Digital phenotyping is currently used with informed consent in research studies but is expected to expand to broader uses in healthcare and direct-to-consumer applications. Digital phenotyping could involve the collection of massive amounts of individual data and potential creation of new categories of health and risk assessment data. Because existing ethical and regulatory frameworks for the provision of mental healthcare do not clearly apply to digital phenotyping, it is critical to consider its possible ethical, legal, and social implications. This paper addresses four major areas where guidelines and best practices will be helpful: transparency, informed consent, privacy, and accountability. It will be important to consider these issues early in the development of this new approach so that its promise is not limited by harmful effects or unintended consequences.

Identifiers

PMID31211249
PMCPMC6550156

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.