ReviewOrthopaedic journal of sports medicine2019
Assessment of Anterior Cruciate Ligament Graft Maturity With Conventional Magnetic Resonance Imaging: A Systematic Literature Review.
Review in Orthopaedic journal of sports medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- No Evidence of Superior Graft Remodeling and Maturation When Adding a Lateral Extra-articular Procedure to Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis of Comparative Studies.The American journal of sports medicine · 2026Pooled it
- Early MRI-based quantitative outcomes are associated with a positive functional performance trajectory from 6 to 24 months post-ACL surgery.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Trial
- Different timing in allograft and autograft maturation after primary anterior cruciate ligament reconstruction does not influence the clinical outcome at mid-long-term follow-up.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Trial
- Randomized controlled trial of all-inside and standard single-bundle anterior cruciate ligament reconstruction with functional, MRI-based graft maturity and patient-reported outcome measures.BMC musculoskeletal disorders · 2022Trial
- "Tension Suspension" Remnant-Preserving ACL Reconstruction Promotes the Early Maturity of the Graft Ligament.Orthopaedic surgery · 2026Article
- Longitudinal Quantitative Mapping of Meniscal Morphological and Signal Intensity Differences After ACL Surgery.The American journal of sports medicine · 2026Article
- Magnetic Resonance Imaging Assessment of Bridge-Enhanced ACL Restoration: An Imaging Atlas of Morphological Features and Healing Trajectories.Orthopaedic journal of sports medicine · 2026Article
- Longitudinal Multiparametric Quantitative MRI Evaluation of Graft Maturity Following Anterior Cruciate Ligament Reconstruction: A One-Year Prospective Observational Study.Diagnostics (Basel, Switzerland) · 2026Article
- Autograft maturation assessed by sequential quantitative MR T2 mapping and its correlation with patient-reported outcomes and return to sports during the first year after anterior cruciate ligament reconstruction.Journal of orthopaedic surgery and research · 2026Article
- Reliability of anterior cruciate ligament (ACL) graft signal intensity measurement on MRI: a novel method with intra- and interrater analysis over a 1-week interval.Polish journal of radiology · 2026Article
- Quantitative assessment of graft maturation after anterior cruciate ligament reconstruction using quadriceps tendon: Insights from ultra short echo time T2∗ mapping.Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology · 2025Article
- Why Should Return to Sport Be Delayed by up to Two Years After ACL Reconstruction? A Narrative Review of the Biological, Surgical and Rehabilitation Evidence.Journal of clinical medicine · 2025Review
- Short graft, short tunnel ACL reconstruction with single hamstring and internal brace leads to comparable outcomes to conventional double hamstring technique: A retrospective study.Journal of experimental orthopaedics · 2025Article
- Sagittal Inclination Angle of the Graft Affects Graft Maturity and Knee Stability After Anterior Cruciate Ligament Reconstruction.Orthopaedic surgery · 2025Article
- Comprehensive evaluation of magnetic resonance imaging sequences for signal intensity based assessment of anterior cruciate ligament healing following surgical treatment.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Association of Graft Maturity on MRI With Return to Sports at 9 Months After Primary Single-Bundle ACL Reconstruction With Autologous Hamstring Graft.Orthopaedic journal of sports medicine · 2024Article
- Response to Comment on: "Return to Sports: A Risky Business? A Systematic Review with Meta-analysis of Risk Factors for Graft Rupture Following ACL Reconstruction".Sports medicine (Auckland, N.Z.) · 2024Article
- LigaNET: A multi-modal deep learning approach to predict the risk of subsequent anterior cruciate ligament injury after surgery.medRxiv : the preprint server for health sciences · 2023Article
- Extracorporeal Shockwave Therapy Improves Outcome after Primary Anterior Cruciate Ligament Reconstruction with Hamstring Tendons.Journal of clinical medicine · 2023Article
- Morphological Changes in the Tibial Tunnel After ACL Reconstruction With the Outside-In Technique and Adjustable Suspensory Fixation.Orthopaedic journal of sports medicine · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMagnetic resonance imaging (MRI) signal intensity (SI) measurements are being used increasingly in both clinical and research studies to assess the maturity of anterior cruciate ligament (ACL) grafts in humans. However, SI in conventional MRI with weighted images is a nonquantitative measure dependent on hardware and software. PURPOSE: To conduct a systematic review of studies that have used MRI SI as a proxy for ACL graft maturity and to identify potential confounding factors in assessing the ACL graft in conventional MRI studies. STUDY
designSystematic review; Level of evidence, 4.
methodsA systematic review was conducted by searching the MEDLINE/PubMed, Scopus, and Cochrane Library electronic databases according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines to identify studies that examined the healing of the intra-articular portion of the ACL graft by assessing SI on MRIs.
resultsA total of 34 studies were selected for inclusion in this systematic review. The MRI acquisition techniques and methods to evaluate the ACL graft SI differed greatly across the studies. No agreement was found regarding the time frames of SI changes in MRI reflecting normal healing of the ACL tendon graft, and the graft SI and clinical outcomes after ACL reconstruction were found to be poorly correlated.
conclusionThe MRI acquisition and evaluation methods used to assess ACL grafts are very heterogeneous, impeding comparisons of SI between successive scans and between independent studies. Therefore, quantitative MRI-based biomarkers of ACL graft healing are greatly needed to guide the appropriate time of returning to sports after ACL reconstruction.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.