Evidence map›Paper›PMID 31211144›Full record

SynthesisBioMed research international2019

Efficacy and Safety of Vonoprazan-Based versus Proton Pump Inhibitor-Based Triple Therapy for

Qiu-Ju Lyu, Qiang-Hong Pu, Xian-Fei Zhong, Jin Zhang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Review
  8. Tegoprazan-Containing Versus Proton Pump Inhibitor-Containing Therapy for First-Line Eradication ofJGH open : an open access journal of gastroenterology and hepatology · 2025
    Review
  9. Article
  10. Article
  11. Comparison of Tegoprazan- and Lansoprazole-Based Fourteen-Day Triple Therapies as First-Line Treatments forThe Korean journal of helicobacter and upper gastrointestinal research · 2024
    Article
  12. [What Is the Optimal Drug Regimen forThe Korean journal of helicobacter and upper gastrointestinal research · 2024
    Article
  13. Vonoprazan-amoxicillin dual regimen withWorld journal of gastroenterology · 2024
    Article
  14. Review
  15. Article
  16. [Potassium-competitive Acid Blockers: A New Therapeutic Strategy forThe Korean journal of helicobacter and upper gastrointestinal research · 2023
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qiu-Ju LyuDepartment of Endocrinology, People's Hospital of Leshan, Sichuan 614000, China.
Qiang-Hong PuDepartment of Pharmacy, People's Hospital of Leshan, Sichuan 614000, China.
Xian-Fei ZhongDepartment of Gastroenterology, People's Hospital of Leshan, Sichuan 614000, China.
Jin ZhangDepartment of Endocrinology, People's Hospital of Leshan, Sichuan 614000, China.ORCID 0000-0002-2037-0426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo compare the efficacy and safety of vonoprazan-based versus proton pump inhibitor (PPI)-based triple therapy in the eradication of

methodsWe performed a systematic search in PubMed, Embase, and the Cochrane Library databases for relevant randomized controlled trials up to March 2019. Studies were included if they compared the efficacy and safety of

resultsThree studies with 897 patients were evaluated in this meta-analysis. The

conclusionsEfficacy of vonoprazan-based triple therapy is superior to that of PPI-based triple therapy for first-line

Indexed as

Helicobacter InfectionsHelicobacter pyloriHumansProton Pump InhibitorsPyrrolesRandomized Controlled Trials as TopicSulfonamides1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamineProton Pump InhibitorsPyrrolesSulfonamides

Identifiers

PMID31211144
PMCPMC6532346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.