Evidence map›Paper›PMID 31211050›Full record

ArticleUrology case reports2019

Complete response to perioperative treatment using nivolumab for metastatic renal cell carcinoma: A case report.

Daiki Ikarashi, Yasuyuki Nakamura, Hitoshi Shimodate, Yoshitaka Usui, Takashi Ujiie, Wataru Obara

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Overview on the role of preoperative therapy in the management of kidney cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Daiki IkarashiDepartment of Urology, Iwate Medical University School of Medicine, 19-1, Uchimaru, Morioka-shi, Iwate, 020-8505, Japan.
Yasuyuki NakamuraDepartment of Pathology, Iwate Prefectural Ofunato Hospital, 10-1, Yamaumagoe, Ofunato-shi, Iwate, 022-8512, Japan.
Hitoshi ShimodateDepartment of Urology, Iwate Medical University School of Medicine, 19-1, Uchimaru, Morioka-shi, Iwate, 020-8505, Japan.
Yoshitaka UsuiDepartment of Urology, Iwate Prefectural Ofunato Hospital, 10-1, Yamaumagoe, Ofunato-shi, Iwate, 022-8512, Japan.
Takashi UjiieDepartment of Urology, Iwate Prefectural Ofunato Hospital, 10-1, Yamaumagoe, Ofunato-shi, Iwate, 022-8512, Japan.
Wataru ObaraDepartment of Urology, Iwate Medical University School of Medicine, 19-1, Uchimaru, Morioka-shi, Iwate, 020-8505, Japan.
Iwate Prefectural Central Hospital · JPIwate Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of 59-year-old woman who has multiple lung metastases with renal cell carcinoma (RCC). She received neoadjuvant therapy using nivolumab following sunitinib. Thereafter, we performed cytoreductive nephrectomy and subsequently administered nivolumab. We also found a high expression of PD-L1 in tumor cell and infiltration of lymphocytes with CD8 expression by immunohistochemistry. A complete response was achieved 4 months after surgery. A perioperative treatment using nivolumab might be useful treatment for metastatic RCC.

Indexed as

Complete responseComputed tomographyCRC-relative proteinCRPCTH&EHematoxylin and eosinIHCIHCsImmunocheckpoint therapiesImmunohistochemistryKarnofsky performance statusKPSNeoadjuvantNivolumabPD-1PD-L1Programmed death-1Programmed death ligand-1RCCRenal cell carcinoma

Identifiers

PMID31211050
PMCPMC6562266
OpenAlexW2913416008

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.