Evidence map›Paper›PMID 31211006›Full record

ArticleGlobal advances in health and medicine2019

Ayurvedic Treatment of Acute Ischemic Stroke: A Prospective Observational Study.

J Aarthi Harini, Avineet Luthra, Shrey Madeka, Prasan Shankar, Pitchaiah Mandava, Ravishankar Pervaje, Sanjith Aaron, Archana Purushotham

Abstract read
In one paragraph

Article in Global advances in health and medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

J Aarthi HariniInstitute for Stem Cell Science and Regenerative Medicine, Bengaluru, India.
Avineet LuthraInstitute for Stem Cell Science and Regenerative Medicine, Bengaluru, India.
Shrey MadekaInstitute for Stem Cell Science and Regenerative Medicine, Bengaluru, India.
Prasan ShankarInstitute of Ayurveda and Integrative Medicine, School of Health Sciences, The University of Trans-Disciplinary Health Sciences and Technology, Bengaluru, India.
Pitchaiah MandavaDepartment of Neurology, Baylor College of Medicine and Michael E. DeBakey VA Medical Center, Houston, Texas.
Ravishankar PervajeInstitute of Ayurveda and Integrative Medicine, School of Health Sciences, The University of Trans-Disciplinary Health Sciences and Technology, Bengaluru, India.
Sanjith AaronDepartment of Neurology, Christian Medical College and Hospital, Vellore, India.
Archana PurushothamInstitute for Stem Cell Science and Regenerative Medicine, Bengaluru, India.ORCID https://orcid.org/0000-0001-8364-6859

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe western medical arsenal for treating stroke is rather limited, and the only treatments shown to improve outcomes are not accessible to most in the third world. Even in the developed world, many patients present too late to receive thrombolysis or thrombectomy. Stroke patients in India commonly use Ayurvedic therapies, but there are no published data regarding the efficacy or safety of these therapies, the latter being of particular concern in acute ischemic stroke (AIS).

objectiveTo obtain preliminary data on the safety and efficacy of stand-alone whole-system Ayurvedic treatment in AIS.

methodsWe present here an observational study prospectively comparing outcomes in 2 cohorts of AIS patients treated with whole-system classical Ayurveda (n = 13) or conservative (nonthrombolytic, noninterventional) western biomedicine (n = 20).

resultsPooled analysis of outcomes did not show statistically significant differences in mortality (15.38% vs 15%,

conclusionsThe safety profiles of classical Ayurveda and conservative western biomedicine in AIS are similar. This is the first ever report of stand-alone Ayurvedic therapy in AIS. Our results support the conduct of a randomized controlled trial to study the efficacy of Ayurvedic treatment of AIS.

Indexed as

Ayurvedacomplementary and alternative medicineintegrative medicineintegrative neurologystroke

Identifiers

PMID31211006
PMCPMC6545648

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.