ReviewTranslational vision science & technology2019
Efficacy of Different Procedures of Intra-Corneal Ring Segment Implantation in Keratoconus: a Systematic Review and Meta-Analysis.
Review in Translational vision science & technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Effects of a Short Daytime Nap on the Cognitive Performance: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Three-Year Visual, Tomographic, and Corvis ST-Derived Biomechanical Outcomes After Combined Intrastromal Ring Implantation and Corneal Collagen Cross-Linking for Keratoconus.Vision (Basel, Switzerland) · 2026Article
- Clinical Outcomes and Complications After INTACS Implantation in Keratoconus: A Systematic Review.Journal of clinical medicine · 2026Review
- Evidence-Based Clinical Practice Guideline for Diagnosis, Treatment, and Follow-Up of Keratoconus Patients.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- CAIRS and nomograms: a narrative review.Eye (London, England) · 2025Review
- Quality of Life in Keratoconus Patients; A Comparison Between Spectacle, Rigid Gas-Permeable Lens, and Corneal Stromal Ring Segment Implantation.Beyoglu eye journal · 2025Article
- Effects and safety of combined corneal collagen crosslinking and intrastromal corneal ring segment treatment in patients with keratoconus: a retrospective study.BMC ophthalmology · 2024Article
- Current concepts in the management of cataract with keratoconus.Indian journal of ophthalmology · 2024Review
- Asymmetric Intrastromal Corneal Ring Segments with Progressive Base Width and Thickness for Keratoconus: Evaluation of Efficacy and Analysis of Epithelial Remodeling.Journal of clinical medicine · 2023Article
- Scheimpflug-Derived Corneal Lower and Higher Order Aberrations Post Intrastromal Corneal Ring Segments for Keratoconus.Vision (Basel, Switzerland) · 2022Article
- Commentary: Femtosecond laser-assisted stromal implants for keratoconus - Customized treatment for the future!Indian journal of ophthalmology · 2021Article
- Femtosecond laser-assisted peripheral additive stromal keratoplasty for treatment of primary corneal ectasia: Preliminary outcomes.Indian journal of ophthalmology · 2021Article
- Trends in surgical procedures and indications for corneal transplantation over 27 years in a tertiary hospital in Japan.Japanese journal of ophthalmology · 2021Article
- Effects of intracorneal ring segments implementation technique and design on corneal biomechanics and keratometry in a personalized computational analysis.Scientific reports · 2021Article
- Evaluation of a new nomogram for Ferrara ring segment implantation in keratoconus.International journal of ophthalmology · 2021Article
- Refractive changes of a new asymmetric intracorneal ring segment with variable thickness and base width: A 2D finite-element model.PloS one · 2021Article
- Corneal Biomechanical Assessment with Ultra-High-Speed Scheimpflug Imaging During Non-Contact Tonometry: A Prospective Review.Clinical ophthalmology (Auckland, N.Z.) · 2021Review
- Asymmetric Thickness Intracorneal Ring Segments for Keratoconus.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Effect of Sequential Intrastromal Corneal Ring Segment Implantation and Corneal Collagen Crosslinking in Corneal Ectasia.Korean journal of ophthalmology : KJO · 2019Article
- Femtosecond laser applications in corneal surgery.Taiwan journal of ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To evaluate the efficacy of the functional, keratometric, and refractive postoperative parameters of intracorneal ring segment (ICRS) implantation in keratoconus and its association with collagen cross-linking (CXL), photorefractive keratectomy (PRK), and intraocular lenses (IOLs). Methods: We conducted a systematic review and meta-analysis on case series published between 2007 and 2017. Results: We included 95 case series with a total of 4560 patients. We included 64 studies of the ICRS procedure, 20 studies of ICRS+CXL, 9 studies of ICRS+CXL+PRK, and 5 studies of ICRS+IOL. We demonstrated an overall improvement of all parameters in all procedures. Cylinder was decreased with an overall effect size (ES) of -1.15 (-1.36 to -0.95; I Conclusions: Although the quality and strength of the data are questionable, ICRS implantation is an effective strategy to preserve visual function in keratoconic patients. Particularly, ICRS+CXL+PRK could be a low invasive procedure to propose to young keratoconic patients. Translational Relevance: To propose an overview of postoperative parameters on each ICRS procedure on keratoconus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.