ReviewAdvances in orthopedics2019
Possible Improvement of the Sagittal Spinopelvic Alignment and Balance through "Locomotion Training" Exercises in Patients with "Locomotive Syndrome": A Literature Review.
Review in Advances in orthopedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Association of the Global Alignment and Proportion Score with Locomotive Syndrome and Health-Related Quality of Life in Community-Dwelling Middle-Aged and Older Adults: A Retrospective Cross-Sectional Study.Spine surgery and related research · 2026Article
- Association between Frailty, Locomotive Syndrome, and Participation Frequency in a Long-Term Care Prevention Program among Community-Dwelling Japanese Older Adults: A Sex-Specific Analysis.Annals of geriatric medicine and research · 2025Article
- Convergent Validity of the Lower Quarter Y Balance Test Against Two-Step and Timed Up and Go Tests in Thai Older Adults with and Without Locomotive Syndrome.International journal of environmental research and public health · 2025Article
- Correlation between metabolic syndrome indicators and locomotive syndrome in Chinese geriatric oncology inpatients.Frontiers in medicine · 2025Article
- Evaluation of Cartilage Degeneration Using MRI T1ρ Mapping after Locomotion Training in Patients with Early Knee Osteoarthritis.Progress in rehabilitation medicine · 2025Article
- Rapamycin mitigates inflammation-mediated disc matrix homeostatic imbalance by inhibiting mTORC1 and inducing autophagy through Akt activation.JOR spine · 2024Article
- Article
- Concepts of Regeneration for Spinal Diseases in 2023.International journal of molecular sciences · 2023Article
- Spinal Sagittal Imbalance is Associated with Vertebral Fracture without a Definite History of Falls: Cross-Sectional, Comparative Study of Cohort with and without a Distal Radius Fracture.Journal of bone metabolism · 2023Article
- Comparative Study for Characteristics of Locomotive Syndrome in Patients with Lumbar Stenosis and Adult Spinal Deformity.Journal of clinical medicine · 2023Article
- Intervertebral disc cell fate during aging and degeneration: apoptosis, senescence, and autophagy.North American Spine Society journal · 2023Article
- Stand-up test predicts occurrence of non-traumatic vertebral fracture in outpatient women with osteoporosis.Journal of bone and mineral metabolism · 2021Article
- Involvement of Autophagy in Rat Tail Static Compression-Induced Intervertebral Disc Degeneration and Notochordal Cell Disappearance.International journal of molecular sciences · 2021Article
- Reductions in the Frequency of Going Out Due to the COVID-19 Pandemic Negatively Affect Patients with Spinal Disorders.Spine surgery and related research · 2021Article
- Characteristics of sagittal spine alignment in female patients with distal radius fractures due to fall.Heliyon · 2020Article
- Age-Related Progression of Degenerative Lumbar Kyphoscoliosis: A Retrospective Study.Spine surgery and related research · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
On the basis of rapid population aging, in 2007, the Japanese Orthopaedic Association (JOA) proposed a new disease concept "locomotive syndrome" as a degenerative condition of reduced mobility due to the impairment of the musculoskeletal system. Worsened locomotive components, which consist of bones, joints, and intervertebral discs, and muscles and nerves, can lead to symptoms such as pain, limited range of motion, malalignment, impaired balance, and difficulty in walking, ultimately resulting in the requirement of nursing care. "Locomotive syndrome" has gained increased interest in Japan but still not worldwide. Hence, in this brief review, we summarize an updated definition, assessment, and management of "locomotive syndrome". The JOA recommends "locomotion training" exercise intervention to be effective in maintaining motor function that comprises two simple exercises-squatting and single-leg standing. However, the extent to which exercises affect "locomotive syndrome" is unknown. Here, we further report hypothesis-generating patient cases who presented the improved sagittal spinopelvic alignment in standing radiographs and postural stability in piezoelectric force-plate measurements through our 6-month "locomotion training" outpatient rehabilitation program. It is noteworthy that "locomotion training" facilitated these improvements despite the presence of specific disorders including thoracic kyphosis and symptomatic lumbar spinal canal stenosis. This raises the need for further investigations to clarify effects of "locomotion training" exercises on the spinal alignment, global balance, and quality of life in patients with "locomotive syndrome".
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.