Evidence map›Paper›PMID 31210810›Full record

ArticleOpen access Macedonian journal of medical sciences2019

The Impact of Physical Exercise on Brain-Derived Neurotrophic Factor (BDNF) Level in Elderly Population.

Fauziah Nuraini Kurdi, Rostika Flora

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Article in Open access Macedonian journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fauziah Nuraini KurdiDepartment of Rehabilitation Medicine, Faculty of Medicine, Sriwijaya University, Palembang, Indonesia.
Rostika FloraFaculty of Public Health, Sriwijaya University, Palembang, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMemory function disorder is a major health problem in geriatric patients. Physical exercise has the potency to decrease the incidence of many degenerative and chronic health problem, related to cognitive deterioration (dementia).

aimThis research aimed to observe the effect of physical exercise in various doses and duration on memory function by analysing the role of Brain-Derived Neurotrophic Factor (BDNF) as a regulatory protein affected by exercise.

methodsThis was an analytical observational study with a cohort design. Thirty participants were included in each group, classified as exercise and non-exercise group. The exercise was in the form of jogging for at least fifteen minutes every day. The observation was done for sixty days. Cognitive function assessment was done by using the Mini-Mental State Examination (MMSE) questionnaire. Meanwhile, the BDNF level was assessed by ELISA. Statistical analysis was done using Independent T-test.

resultsExercise group showed better MMSE score (28.56 ± 1.76), and a higher concentration of BDNF (235.34 ± 12.56 pg/mL), both were statistically significant.

conclusionPhysical exercise was able to maintain geriatric cognitive function performance by BDNF protein regulation.

Indexed as

Brain-Derived Neurotrophic FactorElderlyGeriatricsPhysical exercise

Identifiers

PMID31210810
PMCPMC6560287

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.