Evidence map›Paper›PMID 31210727›Full record

ArticleBiomarker insights2019

Neutrophil to Lymphocyte Ratio is a Predictive Factor of Malignant Potential for Intraductal Papillary Mucinous Neoplasms of the pancreas.

Riki Ohno, Ryuichi Kawamoto, Mami Kanamoto, Jota Watanabe, Masahiko Fujii, Hiromi Ohtani, Masamitsu Harada, Teru Kumagi, Hideki Kawasaki

Abstract read
In one paragraph

Article in Biomarker insights, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Humoral Predictors of Malignancy in IPMN: A Review of the Literature.International journal of molecular sciences · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Riki OhnoDepartment of Gastroenterological Surgery, Ehime Prefectural Central Hospital, Matsuyama-city, Ehime, Japan.
Ryuichi KawamotoDepartment of Community Medicine, Ehime University Graduate School of Medicine, Toon-city, Ehime, Japan.ORCID https://orcid.org/0000-0003-4674-0787
Mami KanamotoDepartment of Gastroenterological Surgery, Ehime Prefectural Central Hospital, Matsuyama-city, Ehime, Japan.
Jota WatanabeDepartment of Gastroenterological Surgery, Ehime Prefectural Central Hospital, Matsuyama-city, Ehime, Japan.
Masahiko FujiiDepartment of Gastroenterological Surgery, Ehime Prefectural Central Hospital, Matsuyama-city, Ehime, Japan.
Hiromi OhtaniDepartment of Gastroenterological Surgery, Ehime Prefectural Central Hospital, Matsuyama-city, Ehime, Japan.
Masamitsu HaradaDepartment of Gastroenterological Surgery, Ehime Prefectural Central Hospital, Matsuyama-city, Ehime, Japan.
Teru KumagiDepartment of Community Medicine, Ehime University Graduate School of Medicine, Toon-city, Ehime, Japan.
Hideki KawasakiDepartment of Gastroenterological Surgery, Ehime Prefectural Central Hospital, Matsuyama-city, Ehime, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intraductal papillary mucinous neoplasms (IPMNs) are cystic neoplasms with the potential for progression to pancreatic cancer. Accurate prediction of the malignant potential is challenging and a proper treatment strategy has not been well established. Preoperative neutrophil-to-lymphocyte ratio (NLR) is a biomarker of the malignant potential in patients with several types of malignancy. We explored malignant potential in patients with IPMN. The present study included 56 patients aged of 73 ± 9 years (mean ± standard deviation) who underwent curative resection for IPMN from 1996 to 2017. We analyzed the relationship between the characteristics including NLR and malignant component for predicting pathological results. The nonmalignant IPMN group (N = 21) included patients with low-grade dysplasia (LGD) and intermediate-grade dysplasia (IGD), and the malignant IPMN group (N = 35) included patients with high-grade dysplasia (HGD) and invasive carcinoma. In a univariate analysis, NLR ⩾ 2.2 (

Indexed as

intraductal papillary mucinous neoplasmmalignant potentialneutrophil-to-lymphocyte ratio

Identifiers

PMID31210727
PMCPMC6552332

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.