ReviewWorld journal of gastroenterology2019
Diagnostic and therapeutic challenges of gastrointestinal angiodysplasias: A critical review and view points.
Review in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Taiwan practical consensus for evaluation and management of small-bowel bleeding.Journal of the Chinese Medical Association : JCMA · 2026Guideline
- Role of thalidomide in angiodysplasia-related gastrointestinal bleeding: a systematic review.Frontiers in gastroenterology (Lausanne, Switzerland) · 2026Pooled it
- Effectiveness of aortic valve replacement in Heyde syndrome: a meta-analysis.European heart journal · 2023Pooled it
- Efficacy and safety of sirolimus in the treatment of gastrointestinal angiodysplasias.World journal of gastroenterology · 2025Trial
- Ten-year follow-up of the first left ventricular assist device implantation program in Chile: a case series.Journal of cardiothoracic surgery · 2026Article
- Right Hemicolectomy for Refractory Hematochezia in Cecal Angiodysplasia After Failed Embolization: A Case Report.Cureus · 2026Article
- Heyde syndrome secondary to hypertrophic obstructive cardiomyopathy: a case report.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Article
- Angiodysplasia as a rare cause of acute hematochezia in a 33-year-old with vascular risk factors: a case report.Frontiers in medicine · 2026Article
- Article
- Endoscopic therapy may be more effective in long-term control of upper gastrointestinal angioectasias when compared with somatostatin analogues.Endoscopy international open · 2026Article
- Obscure gastrointestinal bleeding: case report of ectopic pancreas associated with small bowel angiodysplasia.Journal of surgical case reports · 2026Article
- Imaging and interventions in vascular malformations of the gastrointestinal tract.Abdominal radiology (New York) · 2025Review
- Transcatheter Aortic Valve Replacement Reverses Heyde Syndrome: A Case Report of Severe Aortic Stenosis and Gastrointestinal Bleeding.Journal of clinical medicine · 2025Article
- Advances in gastrointestinal vascular bleeding disorders: Successful sirolimus treatment in colonic angioectasia.World journal of gastroenterology · 2025Review
- Prevalence of hypertension and cardiovascular risk in patients with gastrointestinal angiodysplasia: the role of aortic stiffness and non-dipper blood pressure patterns; predictive value of novel inflammatory biomarkers.Frontiers in cardiovascular medicine · 2025Article
- Heyde Syndrome Unveiled: A Case Report with Current Literature Review and Molecular Insights.International journal of molecular sciences · 2024Review
- Gastrointestinal Angiodysplasia Resolution After Transcatheter Aortic Valve Implantation.JAMA network open · 2024Article
- Endoscopic therapy for gastrointestinal angiodysplasia.The Cochrane database of systematic reviews · 2024Article
- Diagnostic Yield and Outcomes of Small Bowel Capsule Endoscopy in Patients with Small Bowel Bleeding Receiving Antithrombotics.Diagnostics (Basel, Switzerland) · 2024Article
- Impact of percutaneous mitral paravalvular leak closure on the natural history of recurrent gastrointestinal bleeding.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastrointestinal angiodysplasias (GIADs), also called angioectasias, are the most frequent vascular lesions. Its precise prevalence is unknown since most of them are asymptomatic. However, the incidence may be increasing since GIADs affect individuals aged more than 60 years and population life expectancy is globally increasing worldwide. They are responsible of about 5% to 10% of all gastrointestinal bleeding (GIB) cases. Most GIADs are placed in small bowel, where are the cause of 50 to 60% of obscure GIB diagnosed with video capsule endoscopy. They may be the cause of fatal severe bleeding episodes; nevertheless, recurrent overt or occult bleeding episodes requiring repeated expensive treatments and disturbing patient's quality-of-life are more frequently observed. Diagnosis and treatment of GIADs (particularly those placed in small bowel) are a great challenge due to insidious disease behavior, inaccessibility to affected sites and limitations of available diagnostic procedures. Hemorrhagic causality out of the actively bleeding lesions detected by diagnostic procedures may be difficult to establish. No treatment guidelines are currently available, so there is a high variability in the management of these patients. In this review, the epidemiology and pathophysiology of GIADs and the status in the diagnosis and treatment, with special emphasis on small bowel angiodysplasias based on multiple publications, are critically discussed. In addition, a classification of GIADs based on their endoscopic characteristics is proposed. Finally, some aspects that need to be clarified in future research studies are highlighted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.