Evidence map›Paper›PMID 31210676›Full record

Observational studyBulletin of the World Health Organization2019

Impact of the change in WHO's severe pneumonia case definition on hospitalized pneumonia epidemiology: case studies from six countries.

Fiona M Russell, Rita Reyburn, Jocelyn Chan, Evelyn Tuivaga, Ruth Lim, Jana Lai, Hoang Minh Tu Van, Molina Choummanivong, Vanphanom Sychareun, Dung Khu Thi Khanh and 8 more

Abstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in Bulletin of the World Health Organization, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Serum MMP-9 and SAA in the Diagnosis of Severe Pneumonia Caused by Radiotherapy of Esophageal Cancer.Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
  14. COVID-19: What Should the General Practitioner Know?Clinical interventions in aging · 2021
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Fiona M RussellCentre for International Child Health, Department of Paediatrics, University of Melbourne, 50 Flemington Road, Parkville, Melbourne, 3052, Australia.
Rita ReyburnNew Vaccines, Murdoch Children's Research Institute, Melbourne, Australia.
Jocelyn ChanNew Vaccines, Murdoch Children's Research Institute, Melbourne, Australia.
Evelyn TuivagaPaediatrics Department, Ministry of Health and Medical Services, Suva, Fiji.
Ruth LimNew Vaccines, Murdoch Children's Research Institute, Melbourne, Australia.
Jana LaiNew Vaccines, Murdoch Children's Research Institute, Melbourne, Australia.
Hoang Minh Tu VanPaediatric Department, Children's Hospital No. 2, Ho Chi Minh City, Viet Nam.
Molina ChoummanivongFaculty of Postgraduate Studies, University of Health Sciences, Vientiane, Lao People's Democratic Republic.
Vanphanom SychareunFaculty of Postgraduate Studies, University of Health Sciences, Vientiane, Lao People's Democratic Republic.
Dung Khu Thi KhanhNeonatal Department, National Children's Hospital, Hanoi, Viet Nam.
Margaret de CampoDepartment of Radiology, The University of Melbourne, Melbourne, Australia.
Penny EnarsonInternational Union Against Tuberculosis and Lung Disease, Paris, France.
Stephen GrahamCentre for International Child Health, Department of Paediatrics, University of Melbourne, 50 Flemington Road, Parkville, Melbourne, 3052, Australia.
Sophie La VincenteNew Vaccines, Murdoch Children's Research Institute, Melbourne, Australia.
Tuya MunganNew Vaccines, Murdoch Children's Research Institute, Melbourne, Australia.
Claire von MollendorfNew Vaccines, Murdoch Children's Research Institute, Melbourne, Australia.
Grant MackenzieNew Vaccines, Murdoch Children's Research Institute, Melbourne, Australia.
Kim MulhollandNew Vaccines, Murdoch Children's Research Institute, Melbourne, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo quantify the impact of the change in definition of severe pneumonia on documented pneumonia burden.

methodsWe reviewed existing data acquired during observational hospitalized pneumonia studies, before the introduction of the pneumococcal conjugate vaccine, in infants aged 2-23 months from Fiji, Gambia, Lao People's Democratic Republic, Malawi, Mongolia and Viet Nam. We used clinical data to calculate the percentage of all-cause pneumonia hospitalizations with severe pneumonia, and with primary end-point consolidation, according to both the 2005 or 2013 World Health Organization (WHO) definitions. Where population data were available, we also calculated the incidence of severe pneumonia hospitalizations according to the different definitions.

findingsAt six of the seven sites, the percentages of all-cause pneumonia hospitalizations due to severe pneumonia were significantly less (

conclusionThe revision of WHO's definition of severe pneumonia affects pneumonia epidemiology, and hence the interpretation of any pneumonia intervention impact evaluation.

Indexed as

FemaleFijiGambiaHospitalizationHumansIncidenceInfantLaosMalawiMaleMongoliaPneumoniaSeverity of Illness IndexVietnamWorld Health Organization

Identifiers

PMID31210676
PMCPMC6560369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.