Evidence map›Paper›PMID 31210426›Full record

ArticleMicrobial biotechnology2019

Expression fusion immunogen by live attenuated Escherichia coli against enterotoxins infection in mice.

Ni Feng, Weikun Guan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Production of a new tetravalent vaccine targeting fimbriae and enterotoxin of enterotoxigenicCanadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2024
    Article
  3. Article
  4. Pig vaccination strategies based on enterotoxigenic Escherichia coli toxins.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ni FengCollege of Life Science and Resource Environment, Yichun University, Yichun, China.
Weikun GuanCollege of Life Science and Resource Environment, Yichun University, Yichun, China.ORCID 0000-0003-0669-5141
Yichun University · CN

Funding

Jiangxi Province Department of Education Science and Technology Project GJJ170917Yichun University 113-3350100050
6 · The paper itself

Abstract

Previous epidemiological studies have shown that enterotoxins from enterotoxigenic Escherichia coli (ETEC) appear to be the most important causes of neonatal piglet and porcine post-weaning diarrhoea (PWD). Thus, it is necessary to develop an effective vaccine against ETEC infection. In the present study, the Kil cassette was inserted into the pseudogene yaiT by homologous recombination to create an attenuated E. coli double selection platform O142(yaiT-Kil). After that, PRPL-Kil was replaced with a fusion gene (LTA1-STa

Indexed as

Administration, OralAnimalsAntibodies, BacterialAntigens, BacterialDiarrheaEnterotoxigenic Escherichia coliEnterotoxinsEscherichia coli InfectionsEscherichia coli VaccinesFecesImmunity, CellularImmunoglobulin A, SecretoryImmunoglobulin GMice, Inbred BALB CRecombinant Fusion ProteinsSwineAntibodies, BacterialAntigens, BacterialEnterotoxinsEscherichia coli VaccinesImmunoglobulin A, SecretoryImmunoglobulin GRecombinant Fusion ProteinsVaccines, AttenuatedVaccines, Synthetic

Identifiers

PMID31210426
PMCPMC6680629
OpenAlexW2950286179

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.