Evidence map›Paper›PMID 31210096›Full record

ArticleJournal of neurotrauma2019

Exposure to Blast Overpressure Impairs Cerebral Microvascular Responses and Alters Vascular and Astrocytic Structure.

Rania Abutarboush, Ming Gu, Usmah Kawoos, Saad H Mullah, Ye Chen, Samantha Y Goodrich, Margaret Lashof-Sullivan, Richard M McCarron, Jonathan K Statz, Randy S Bell and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurotrauma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Rania AbutarboushNeurotrauma Department, Naval Medical Research Center, Silver Spring, Maryland.
Ming GuNeurotrauma Department, Naval Medical Research Center, Silver Spring, Maryland.
Usmah KawoosNeurotrauma Department, Naval Medical Research Center, Silver Spring, Maryland.
Saad H MullahNeurotrauma Department, Naval Medical Research Center, Silver Spring, Maryland.
Ye ChenNeurotrauma Department, Naval Medical Research Center, Silver Spring, Maryland.
Samantha Y GoodrichNeurotrauma Department, Naval Medical Research Center, Silver Spring, Maryland.
Margaret Lashof-SullivanNeurotrauma Department, Naval Medical Research Center, Silver Spring, Maryland.
Richard M McCarronNeurotrauma Department, Naval Medical Research Center, Silver Spring, Maryland.
Jonathan K StatzNeurotrauma Department, Naval Medical Research Center, Silver Spring, Maryland.
Randy S BellNeurosurgery Department, Walter Reed National Military Medical Center, Bethesda, Maryland.
James R StoneDepartment of Radiology and Medical Imaging, University of Virginia Medical Center, Charlottesville, Virginia.
Stephen T AhlersNeurotrauma Department, Naval Medical Research Center, Silver Spring, Maryland.
Henry M. Jackson Foundation · USNaval Medical Research Command · USUniversity of Virginia Medical Center · USWalter Reed National Military Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to blast overpressure may result in cerebrovascular impairment, including cerebral vasospasm. The mechanisms contributing to this vascular response are unclear. The aim of this study was to evaluate the relationship between blast and functional alterations of the cerebral microcirculation and to investigate potential underlying changes in vascular microstructure. Cerebrovascular responses were assessed in sham- and blast-exposed male rats at multiple time points from 2 h through 28 days after a single 130-kPa (18.9-psi) exposure. Pial microcirculation was assessed through a cranial window created in the parietal bone of anesthetized rats. Pial arteriolar reactivity was evaluated

Indexed as

Cerebrovascular CirculationAnimalsArteriolesAstrocytesBlast InjuriesBrain Injuries, TraumaticMaleRatsRats, Long-Evansblast overpressurecerebrovascular reactivityin vivo studiesmicrocirculationvascular injury

Identifiers

PMID31210096
PMCPMC6818492
OpenAlexW2950945124

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.