Evidence map›Paper›PMID 31210093›Full record

Observational studyJournal of neurotrauma2019

Favorable Functional Recovery in Severe Traumatic Brain Injury Survivors beyond Six Months.

Tiffany E Wilkins, Sue R Beers, Allison J Borrasso, Jordan Brooks, Matthew Mesley, Ross Puffer, Yue-Fang Chang, David O Okonkwo, Ava M Puccio

Abstract readObservational Study
In one paragraph

Observational study in Journal of neurotrauma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Severe traumatic brain injury and long-term survival: a meta-analysis on life expectancy and mortality trends.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  2. Long-term life expectancy in severe traumatic brain injury: a systematic review.European journal of physical and rehabilitation medicine · 2024
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Observational
  7. Preservation of anticorrelated brain networks predicts recovery after traumatic brain injury.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
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  15. Article
  16. Article
  17. Review
  18. Article
  19. Traumatic brain injuries: a neuropsychological review.Frontiers in behavioral neuroscience · 2024
    Review
  20. Computational Prognostic Modeling in Traumatic Brain Injury.Advances in experimental medicine and biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tiffany E WilkinsDepartment of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Sue R BeersDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Allison J BorrassoDepartment of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Jordan BrooksDepartment of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Matthew MesleyDepartment of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Ross PufferDepartment of Neurological Surgery, Mayo Clinic, Rochester, Minnesota.
Yue-Fang ChangDepartment of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
David O OkonkwoDepartment of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Ava M PuccioDepartment of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

Funding

UNIVERSITY OF PITTSBURGH BRAIN TRAUMA RESEARCH CENTERP50NS030318 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEKOSKY, STEVEN T. · 1995 to 2007
$8.9M
TBI, Amyloid Metabolism and Statin TherapyP01NS030318 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOCHANEK, PATRICK M · 2008 to 2010
$3.7M
Transcriptomics in Traumatic Brain Injury: Relationship to Brain Oxygenation and OutcomesR00NR013176 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PUCCIO, AVA M. · 2014 to 2016
$724k
NINDS NIH HHS P01 NS030318NINDS NIH HHS P50 NS030318NINR NIH HHS R00 NR013176
6 · The paper itself

Abstract

Favorable long-term functional outcomes after severe traumatic brain injury (TBI) may be underestimated. We analyzed 24-month functional outcomes from a consecutive series of severe TBI survivors. A prospective, observational database of severe TBI survivors from a single institution was analyzed. Glasgow Outcome Scale-Extended (GOS-E) scores were obtained at 3, 6, 12, and 24 months post-injury. GOS-E scores were dichotomized into unfavorable and favorable outcomes, and the proportion of survivors changing from unfavorable to favorable outcomes was calculated using Wilcoxon signed-rank tests. Surviving adults (

Indexed as

Brain Injuries, TraumaticRecovery of FunctionAdultAgedFemaleGlasgow Outcome ScaleHumansLongitudinal StudiesMaleMiddle AgedPrognosisSurvivorsGlasgow Outcome Scale-Extendedlong-term functional statustraumatic brain injury

Identifiers

PMID31210093
PMCPMC6818481

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.