Evidence map›Paper›PMID 31210022›Full record

ArticleMolecular genetics & genomic medicine2019

Incidence, demographic characteristics, and geographic distribution of sickle cell trait and sickle cell anemia births in Michigan, 1997-2014.

Sarah L Reeves, Hannah K Jary, Jennifer P Gondhi, Mary Kleyn, Kayte Spector-Bagdady, Kevin J Dombkowski

Abstract read
In one paragraph

Article in Molecular genetics & genomic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah L ReevesDepartment of Pediatrics, Susan B. Meister Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-9145-0183
Hannah K JaryDepartment of Pediatrics, Susan B. Meister Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, Michigan.
Jennifer P GondhiDepartment of Pediatrics, Susan B. Meister Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, Michigan.
Mary KleynMichigan Department of Health and Human Services, Lansing, Michigan.
Kayte Spector-BagdadyDepartment of Obstetrics and Gynecology, Center for Bioethics & Social Sciences in Medicine, University of Michigan, Ann Arbor, Michigan.
Kevin J DombkowskiDepartment of Pediatrics, Susan B. Meister Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, Michigan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study describes the incidence, demographic characteristics, and geographic distribution of sickle cell anemia (SCA) and sickle cell trait births in Michigan.

methodsMichigan newborn screening records and birth certificates (1997-2014) were used to identify sickle cell trait and SCA births, as well as demographic characteristics and mother's residential address. Incidence was calculated overall and by county.

resultsDuring the study period, there were 592 SCA births and 33,404 sickle cell trait births in Michigan. The majority of SCA (86.3%) and trait (80.2%) cases were among children who were black. Children with SCA were born in 23% of Michigan counties; children with trait were born in 93%.

conclusionCompared to SCA, sickle cell trait births occur at 50-fold greater incidence and have a substantially expanded geographic distribution. Further research is necessary to understand the most appropriate and impactful use of resources to increase the proportion of families and adults that are aware of their sickle cell trait status.

Indexed as

Anemia, Sickle CellEthnicityFemaleGeographyHumansIncidenceInfant, NewbornMaleMichiganNeonatal ScreeningPrevalenceRacial GroupsSex FactorsSickle Cell TraitMichigannewborn screeningsickle cell anemiasickle cell trait

Identifiers

PMID31210022
PMCPMC6687629

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