ArticlePharmacoepidemiology and drug safety2019
Adverse drug event patterns experienced by patients with diabetes: A diary study in primary care.
Article in Pharmacoepidemiology and drug safety, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Retrospective Analysis of Adverse Drug Reactions in Patients with Type 2 Diabetes Mellitus and Development of a Risk Prediction Model.International journal of general medicine · 2026Article
- Diabetes mellitus increases risk of adverse drug reactions and death in hospitalised older people: the SENATOR trial.European geriatric medicine · 2024Article
- Sex Differences in Adverse Drug Reactions of Metformin: A Longitudinal Survey Study.Drug safety · 2020Article
- Adverse drug event patterns experienced by patients with diabetes: A diary study in primary care.Pharmacoepidemiology and drug safety · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLittle is known about adverse drug events (ADEs) experienced over time during chronic drug use. The purpose of this study was to assess ADE patterns experienced by patients with diabetes.
methodsPatients who received an oral glucose-lowering drug completed a daily diary for 13 weeks. The diary asked for experienced symptoms and whether patients related these symptoms to any drug they used. Summaries of Product Characteristics were used to check whether the ADEs were known adverse drug reactions (ADRs) of the drugs used. Patterns of weekly occurring ADEs were assessed with descriptive statistics.
resultsWe included 78 patients. Almost half of them reported at least one ADE (N = 36; 46%). In total, 80 ADEs were reported. Of these ADEs, 71 (90%) were known ADRs. ADEs lasted less than 1 week in 27 cases (34%) and between 2 and 12 weeks in 15 cases (19%). The remaining ADEs fluctuated (16 cases; 20%) or persisted (22 cases; 28%) during the entire study period.
conclusionsADEs experienced by patients with diabetes can fluctuate or persist over long periods of drug use.
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