Evidence map›Paper›PMID 31209693›Full record

ReviewMycopathologia2019

Attack, Defend and Persist: How the Fungal Pathogen Candida auris was Able to Emerge Globally in Healthcare Environments.

Auke W de Jong, Ferry Hagen

Open access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 94 citations in OpenAlex.

  1. Journal of fungi (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Repositioning Antimicrobial Peptides Against WHO-Priority Fungi.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Genomic Dynamics of the EmergentOpen forum infectious diseases · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Microbiology spectrum · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Functional Redundancy inResearch square · 2024
    Article
  17. Functional Redundancy inbioRxiv : the preprint server for biology · 2024
    Article
  18. The Gordian Knot ofPathogens (Basel, Switzerland) · 2023
    Review
  19. SevereJournal of intensive medicine · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Auke W de JongDepartment of Medical Mycology, Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0002-0914-4612
Ferry HagenDepartment of Medical Mycology, Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands. f.hagen@wi.knaw.nl.ORCID http://orcid.org/0000-0002-5622-1916
University Medical Center Utrecht · NLWesterdijk Fungal Biodiversity Institute · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Within a decade after its first description, the multidrug-resistant yeast Candida auris has emerged globally as a nosocomial pathogen causing difficult to control outbreaks. This, together with the alarmingly high mortality rate of up to 66% associated with C. auris candidemia, calls for a better understanding of its virulence traits and routes of transmission. Unlike other clinically relevant Candida species, C. auris seems to have the unique ability to be easily transmitted between patients. Although initially thought to express fewer virulence traits than Candida albicans, recent genomic insights suggest C. auris to possess these traits to a much more similar extent. This review highlights the virulence traits C. auris expresses to attack the host, defend itself against antimicrobial agents and to persist within the healthcare environment.

Indexed as

CandidaCandidemiaCommunicable Diseases, EmergingCross InfectionDisease OutbreaksDisease Transmission, InfectiousDrug Resistance, Multiple, FungalGlobal HealthHumansVirulenceVirulence FactorsVirulence FactorsAnimal modelsBiofilmsCandida aurisDisinfectantsGenomicsMorphogenesisPathogenicityPhenotypic switchResistanceVirulence traits

Identifiers

PMID31209693
OpenAlexW2950379126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.