Evidence map›Paper›PMID 31209564›Full record

ReviewCurrent genetics2020

Regulation of cytokinesis: FtsZ and its accessory proteins.

Mingzhi Wang, Chao Fang, Bo Ma, Xiaoxing Luo, Zheng Hou

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Gaseous NOScientific reports · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Molecular Characterization of theAntibiotics (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mingzhi WangDepartment of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, China.
Chao FangDepartment of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, China.
Bo MaDepartment of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, China.
Xiaoxing LuoDepartment of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, China.
Zheng HouDepartment of Pharmacology, School of Pharmacy, Fourth Military Medical University, Xi'an, China. hzh_0001@163.com.ORCID http://orcid.org/0000-0002-0358-7869
Air Force Medical University · CN

Funding

National Natural Science Foundation of China 81001460National Natural Science Foundation of China 81471997National Natural Science Foundation of China 81673477
6 · The paper itself

Abstract

Bacterial cell division is a highly controlled process regulated accurately by a diverse array of proteins spatially and temporally working together. Among these proteins, FtsZ is recognized as a cytoskeleton protein because it can assemble into a ring-like structure called Z-ring at midcell. Z-ring recruits downstream proteins, thus forming a multiprotein complex termed the divisome. When the Z-ring scaffold is established and the divisome matures, peptidoglycan (PG) biosynthesis and chromosome segregation are triggered. In this review, we focus on multiple interactions between FtsZ and its accessory proteins in bacterial cell cytokinesis, including FtsZ localization, Z-ring formation and stabilization, PG biosynthesis, and chromosome segregation. Understanding the interactions among these proteins may help discover superior targets on treating bacterial infectious diseases.

Indexed as

Bacterial Physiological PhenomenaBacterial ProteinsCell DivisionCytokinesisCytoskeletal ProteinsEnergy MetabolismProtein BindingProtein StabilityProtein TransportStructure-Activity RelationshipBacterial ProteinsCytoskeletal ProteinsFtsZ protein, BacteriaBacterial cytokinesisDivision proteinDivisomeFtsZZ-ring

Identifiers

PMID31209564
OpenAlexW2953205113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.