ArticleScientific reports2019
Comparative genomics of chytrid fungi reveal insights into the obligate biotrophic and pathogenic lifestyle of Synchytrium endobioticum.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 56 citations in OpenAlex.
- Eukaryotic metagenome-assembled genomes recovered from deep metagenomic sequencing of the seagrass,Microbial genomics · 2026Article
- Molecular Insights intoLife (Basel, Switzerland) · 2026Article
- Single-cell genomics, metagenomics, and transcriptomics ofAquatic ecology · 2026Article
- A genomic perspective on fungal diversity and evolution.Nature reviews. Microbiology · 2025Review
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- Identification of a Highly VirulentPlants (Basel, Switzerland) · 2025Article
- Decoding microbiome responses to quarantine potato wart disease: first insights into suppression and biocontrol by full-length 16S rRNA gene profiling and functional prediction.Frontiers in plant science · 2025Article
- The impact of salt-tolerant plants on soil nutrients and microbial communities in soda saline-alkali lands of the Songnen plain.Frontiers in microbiology · 2025Article
- A target enrichment approach for enhanced recovery of Synchytrium endobioticum nuclear genome sequences.PloS one · 2024Article
- Potato Wart Isolates from Europe and North America Form Distinct Clusters of Genetic Variation.Life (Basel, Switzerland) · 2023Article
- Two-speed genome evolution drives pathogenicity in fungal pathogens of animals.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- A Genome Sequence Assembly of the Phototactic and Optogenetic Model Fungus Blastocladiella emersonii Reveals a Diversified Nucleotide-Cyclase Repertoire.Genome biology and evolution · 2022Article
- Synchytrium endobioticum, the potato wart disease pathogen.Molecular plant pathology · 2022Review
- Article
- Ecological succession of fungal and bacterial communities in Antarctic mosses affected by a fairy ring disease.Extremophiles : life under extreme conditions · 2021Article
- Far-Red Absorbing Rhodopsins, Insights From Heterodimeric Rhodopsin-Cyclases.Frontiers in molecular biosciences · 2021Review
- A Call for a Better Understanding of Aquatic Chytrid Biology.Frontiers in fungal biology · 2021Article
- Metagenomics survey unravels diversity of biogas microbiomes with potential to enhance productivity in Kenya.PloS one · 2021Article
- A putative origin of the insect chemosensory receptor superfamily in the last common eukaryotic ancestor.eLife · 2020Article
- NeoR, a near-infrared absorbing rhodopsin.Nature communications · 2020Article
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synchytrium endobioticum is an obligate biotrophic soilborne Chytridiomycota (chytrid) species that causes potato wart disease, and represents the most basal lineage among the fungal plant pathogens. We have chosen a functional genomics approach exploiting knowledge acquired from other fungal taxa and compared this to several saprobic and pathogenic chytrid species. Observations linked to obligate biotrophy, genome plasticity and pathogenicity are reported. Essential purine pathway genes were found uniquely absent in S. endobioticum, suggesting that it relies on scavenging guanine from its host for survival. The small gene-dense and intron-rich chytrid genomes were not protected for genome duplications by repeat-induced point mutation. Both pathogenic chytrids Batrachochytrium dendrobatidis and S. endobioticum contained the largest amounts of repeats, and we identified S. endobioticum specific candidate effectors that are associated with repeat-rich regions. These candidate effectors share a highly conserved motif, and show isolate specific duplications. A reduced set of cell wall degrading enzymes, and LysM protein expansions were found in S. endobioticum, which may prevent triggering plant defense responses. Our study underlines the high diversity in chytrids compared to the well-studied Ascomycota and Basidiomycota, reflects characteristic biological differences between the phyla, and shows commonalities in genomic features among pathogenic fungi.
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