Evidence map›Paper›PMID 31209195›Full record

ArticleThe American journal of case reports2019

Epithelioid Hemangioendothelioma: A Rare Case of an Aggressive Vascular Malignancy.

Meghan Lytle, Sunil Daniel Bali, Yehuda Galili, Brittany Bednov, Rodrigo M Murillo Alvarez, Stephen J Carlan, Mario Madruga

Open access · hybridAbstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Meghan LytleDepartment of Internal Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Sunil Daniel BaliDivision of Pulmonology, Orlando Regional Healthcare, Orlando, FL, USA.
Yehuda GaliliDepartment of Internal Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Brittany BednovDepartment of Internal Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Rodrigo M Murillo AlvarezDepartment of Pathology, Orlando Regional Healthcare, Orlando, FL, USA.
Stephen J CarlanDepartment of Obstetrics and Gynecology, Division of Academic Affairs and Research, Orlando Regional Healthcare, Orlando, FL, USA.
Mario MadrugaDepartment of Internal Medicine, Orlando Regional Healthcare, Orlando, FL, USA.
Orlando Health · USRegional Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Epithelioid hemangioendothelioma (EHE) is a rare vascular malignancy that occurs in multiple organs and tissues with a predilection for the extremities, bone, liver, and lung. It is often characterized by a clinically indolent course, delayed diagnosis, and unestablished standardized treatment options. CASE REPORT A 46-year-old female presented with a 2-month history of right shoulder and arm pain. Imaging revealed involvement of the humerus, lung, liver; and brain and biopsies of both the lung and humerus were performed. A diagnosis of epithelioid hemangioendothelioma was confirmed and the patient received radiation therapy to the right humerus and brain stereotactic radiosurgery. She was scheduled to begin palliative chemotherapy with doxorubicin but developed complications and never received chemotherapeutic agents. She died 5.5 months from her first admission with widespread metastasis. CONCLUSIONS Epithelioid hemangioendothelioma (EHE) is typically a low-to-intermediate grade vascular malignancy, but, as seen in this case, can be aggressive. In the future, diagnosis, prognosis, and treatment may improve using genetic or immune therapy considering a structural chromosomal translocation has been identified.

Indexed as

HumerusBone NeoplasmsBrain NeoplasmsFatal OutcomeFemaleHemangioendothelioma, EpithelioidHumansLiver NeoplasmsLung NeoplasmsMiddle Aged

Identifiers

PMID31209195
PMCPMC6597141
OpenAlexW2951648671

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.