Evidence map›Paper›PMID 31209141›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

Complement in Motion: The Evolution of CD46 from a Complement Regulator to an Orchestrator of Normal Cell Physiology.

M Kathryn Liszewski, Claudia Kemper

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. The multiverse of CD46 and oncologic interactions.The Journal of clinical investigation · 2025
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Human gene therapy · 2022
    Article
  10. Safe and efficientMolecular therapy. Methods & clinical development · 2022
    Article
  11. Journal of virology · 2022
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Complement's favourite organelle-Mitochondria?British journal of pharmacology · 2021
    Review
  17. Oncolytic Virotherapy and Microenvironment in Multiple Myeloma.International journal of molecular sciences · 2021
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

M Kathryn LiszewskiDivision of Rheumatology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110; kliszews@wustl.edu Claudia.kemper@nih.gov.ORCID 0000-0002-8859-0230
Claudia KemperImmunology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892; kliszews@wustl.edu Claudia.kemper@nih.gov.ORCID 0000-0003-4196-1417
National Institutes of Health · USWashington University in St. Louis · US

Funding

The role of the intracellular complement system - the complosome - in Th1 biologyZIAHL006223 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KEMPER, CLAUDIA · 2017 to 2025
$16.9M
INTRACELLULAR C3 PROTEINS: SOURCE, COMPOSITION, TRAFFICKING AND FUNCTIONR01GM099111 · NIGMS · WASHINGTON UNIVERSITY · PI ATKINSON, JOHN · 2011 to 2019
$2.7M
Intramural NIH HHS Z99 HL999999NIGMS NIH HHS R01 GM099111
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBiological EvolutionCell Physiological PhenomenaComplement ActivationComplement System ProteinsHost-Pathogen InteractionsHumansImmunologic Deficiency SyndromesImmunomodulationLymphocyte ActivationMembrane Cofactor ProteinTh1 CellsComplement System ProteinsMembrane Cofactor Protein

Identifiers

PMID31209141
PMCPMC7458270
OpenAlexW2952343158

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.