ArticleThe Journal of biological chemistry2019
Acetyl-CoA carboxylase 1-dependent lipogenesis promotes autophagy downstream of AMPK.
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Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)Autophagy · 2021Guideline
- Article
- Fatty acid synthesis supports tumor progression through facilitating the activity of TORC1 signaling.Cell death & disease · 2026Article
- Sodium butyrate-induced autophagy in colorectal cancer unveils the Ca²⁺/CaMKKβ signaling pathway as a potential therapeutic target.Scientific reports · 2025Article
- Acetyl-CoA carboxylase maintains energetic balance for functional oogenesis.Nature communications · 2025Article
- Phospholipid Scramblase Activity of VDAC Dimers: New Implications for Cell Death, Autophagy and Ageing.Biomolecules · 2024Review
- MFN2 suppresses the accumulation of lipid droplets and the progression of clear cell renal cell carcinoma.Cancer science · 2024Article
- Millifluidic magnetophoresis-based chip for age-specific fractionation: evaluating the impact of age on metabolomics and gene expression in yeast.Lab on a chip · 2024Article
- Nitrogen limitation-induced adaptive response and lipogenesis in the Antarctic yeastFrontiers in microbiology · 2024Article
- Nutlin-3a induces KRAS mutant/p53 wild type lung cancer specific methuosis-like cell death that is dependent on GFPT2.Journal of experimental & clinical cancer research : CR · 2023Article
- The sensor histidine kinase (SLN1) and acetyl-CoA carboxylase (ACC1) coordinately regulate the response ofApplied and environmental microbiology · 2023Article
- De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics.Nature communications · 2023Article
- Swietenine Alleviates Nonalcoholic Fatty Liver Disease in Diabetic Mice via Lipogenesis Inhibition and Antioxidant Mechanisms.Antioxidants (Basel, Switzerland) · 2023Article
- Knocking out central metabolism genes to identify new targets and alternating substrates to improve lipid synthesis inFrontiers in bioengineering and biotechnology · 2023Article
- Lipid and glucose metabolism in senescence.Frontiers in nutrition · 2023Review
- GATA-type transcriptional factor SpGAT1 interacts with SpMIG1 and promotes lipid accumulation in the oleaginous yeastBiotechnology for biofuels and bioproducts · 2022Article
- Article
- Paired related homeobox 1 attenuates autophagy via acetyl-CoA carboxylase 1-regulated fatty acid metabolism in salivary adenoid cystic carcinoma.FEBS open bio · 2022Article
- Lipogenesis inhibitors: therapeutic opportunities and challenges.Nature reviews. Drug discovery · 2022Review
- LncRNA MEG3 up-regulates SIRT6 by ubiquitinating EZH2 and alleviates nonalcoholic fatty liver disease.Cell death discovery · 2022Article
Corrections and comments
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Authors and funding
24 authors at 4 institutions in 3 countries.
Angelina S GrossInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Andreas ZimmermannInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria; Central Lab Gracia, NAWI Graz, University of Graz, 8010 Graz, Austria.
Tobias PendlInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Sabrina SchroederInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria; BioTechMed-Graz, 8010 Graz, Austria.
Hannes SchoenlechnerInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Oskar KnittelfelderMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Laura LamplmayrInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Ana SantisoInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Andreas AufschnaiterInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria; Department of Molecular Biosciences, Wenner-Gren Institute, Stockholm University, 114 19 Stockholm, Sweden.
Daniel WaltenstorferInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Sandra Ortonobes LaraInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Sarah StryeckGottfried Schatz Research Center for Cell Signaling, Metabolism, and Aging, Institute of Molecular Biology and Biochemistry, Medical University of Graz, 8036 Graz, Austria.
Christina KastInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Christoph RuckenstuhlInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Sebastian J HoferInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria; BioTechMed-Graz, 8010 Graz, Austria.
Birgit MichelitschInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria; Division of Plastic, Aesthetic, and Reconstructive Surgery, Department of Surgery, Medical University of Graz, 8036 Graz, Austria.
Martina WoelflingsederInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Rolf MüllerHelmholtz Institute for Pharmaceutical Research Saarland, 66123 Saarbrücken, Germany.
Didac Carmona-GutierrezInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Tobias MadlBioTechMed-Graz, 8010 Graz, Austria; Gottfried Schatz Research Center for Cell Signaling, Metabolism, and Aging, Institute of Molecular Biology and Biochemistry, Medical University of Graz, 8036 Graz, Austria.
Sabrina BüttnerInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria; Department of Molecular Biosciences, Wenner-Gren Institute, Stockholm University, 114 19 Stockholm, Sweden.
Kai-Uwe FröhlichInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria.
Andrej ShevchenkoMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Tobias EisenbergInstitute of Molecular Biosciences, NAWI Graz, University of Graz, 8010 Graz, Austria; Central Lab Gracia, NAWI Graz, University of Graz, 8010 Graz, Austria; BioTechMed-Graz, 8010 Graz, Austria. Electronic address: tobias.eisenberg@uni-graz.at.
University of Graz · ATMax Planck Institute of Molecular Cell Biology and Genetics · DEMedical University of Graz · ATHelmholtz Institute for Pharmaceutical Research Saarland · DE
Funding
Austrian Science Fund FWF I 3792Austrian Science Fund FWF P 27183Austrian Science Fund FWF P 28854Austrian Science Fund FWF W 1226
Abstract
Autophagy, a membrane-dependent catabolic process, ensures survival of aging cells and depends on the cellular energetic status. Acetyl-CoA carboxylase 1 (Acc1) connects central energy metabolism to lipid biosynthesis and is rate-limiting for the
Indexed as
AutophagyLipogenesisAcetatesAcetyl-CoA CarboxylaseMacrolidesMutagenesis, Site-DirectedProtein Serine-Threonine KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAcetatesAcetyl-CoA CarboxylaseMacrolidesProtein Serine-Threonine KinasesSaccharomyces cerevisiae ProteinsSNF1-related protein kinasessoraphen AAcc1acetateacetyl-CoA carboxylase 1acetyl coenzyme A (acetyl-CoA)agingAMPKautophagylipid metabolismlipogenesisoleateSnf1yeast
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.