Evidence map›Paper›PMID 31209014›Full record

ArticleAntimicrobial agents and chemotherapy2019

Efflux-Mediated Resistance to New Oxazolidinones and Pleuromutilin Derivatives in Escherichia coli with Class Specificities in the Resistance-Nodulation-Cell Division-Type Drug Transport Pathways.

Sabine Schuster, Martina Vavra, Winfried V Kern

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sabine SchusterDivision of Infectious Diseases, Department of Medicine II, University Hospital and Medical Center, Freiburg, Germany sabine.schuster@uniklinik-freiburg.de.
Martina VavraDivision of Infectious Diseases, Department of Medicine II, University Hospital and Medical Center, Freiburg, Germany.
Winfried V KernDivision of Infectious Diseases, Department of Medicine II, University Hospital and Medical Center, Freiburg, Germany.
University Medical Center Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A major contribution of the resistance-nodulation-cell division (RND)-transporter AcrB to resistance to oxazolidinones and pleuromutilin derivatives in

Indexed as

Anti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsBiological TransportCell DivisionDiterpenesDrug Resistance, Multiple, BacterialEscherichia coliEscherichia coli ProteinsMembrane Transport ProteinsMicrobial Sensitivity TestsMutationOxazolidinonesPleuromutilinsPolycyclic CompoundsSignal TransductionAcrB protein, E coliAnti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsDiterpenesEscherichia coli ProteinsMdtF protein, E coliMembrane Transport ProteinsOxazolidinonesPleuromutilinsPolycyclic CompoundsAcrBeffluxoxazolidinonespleuromutilinsRND-type transporterYhiV (MdtF)

Identifiers

PMID31209014
PMCPMC6709491
OpenAlexW2949725538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.