Evidence map›Paper›PMID 31208430›Full record

ArticleBMC infectious diseases2019

Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome - a case report of a complicated scenario.

Gopalan Narendran, Deivide Oliveira-de-Souza, Caian L Vinhaes, Kevan Akrami, Kiyoshi F Fukutani, Kesavamurthy Banu, Padmapriyadarsini Chandrasekaran, Narayanan Ravichandran, Irini Sereti, Soumya Swaminathan and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gopalan NarendranNational Institute for Research in Tuberculosis, Chennai, 600031, India.
Deivide Oliveira-de-SouzaInstituto GonçaloMoniz, Fundação Oswaldo Cruz, Salvador, 40296-710, Brazil.
Caian L VinhaesInstituto GonçaloMoniz, Fundação Oswaldo Cruz, Salvador, 40296-710, Brazil.
Kevan AkramiInstituto GonçaloMoniz, Fundação Oswaldo Cruz, Salvador, 40296-710, Brazil.
Kiyoshi F FukutaniInstituto GonçaloMoniz, Fundação Oswaldo Cruz, Salvador, 40296-710, Brazil.
Kesavamurthy BanuInstitute of Neurology, Madras Medical College, Chennai, India.
Padmapriyadarsini ChandrasekaranNational Institute for Research in Tuberculosis, Chennai, 600031, India.
Narayanan RavichandranGovernment Hospital of Thoracic Medicine, Tambaram, Chennai, India.
Irini SeretiNational Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Soumya SwaminathanNational Institute for Research in Tuberculosis, Chennai, 600031, India.
Bruno B AndradeInstituto GonçaloMoniz, Fundação Oswaldo Cruz, Salvador, 40296-710, Brazil. Bruno.andrade@bahia.fiocruz.br.ORCID http://orcid.org/0000-0001-6833-3811

Funding

Immunopathogenic Mechanisms of Human Immunodeficiency Virus (HIV) DiseaseZIAAI001121 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SERETI, IRINI · 2010 to 2025
$27.2M
Inflammatory determinants of disease severity and treatment outcome in TB patientsU01AI115940 · NIAID · UNIVERSITY OF CAPE TOWN · PI SHER, ALAN, WILKINSON, ROBERT JOHN · 2015 to 2019
$1.1M
National Institute of Allergy and Infectious Diseases Intramural-to-IndiaNational Institute of Allergy and Infectious Diseases U01AI115940NIAID NIH HHS U01 AI115940
6 · The paper itself

Abstract

backgroundTuberculosis (TB)-associated Immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response in TB patients with advanced human immunodeficiency virus coinfection, after antiretroviral therapy commencement. CASE PRESENTATION: We present a rare case of a 51-year-old woman living with HIV who developed a series of TB-IRIS events occurring at multiple sites sequentially, highlighting the clinical complexity in diagnosis and management.

conclusionThis case illustrates how complicated a clinical scenario of successive TB-IRIS episodes can be, in terms of clinical management.

Indexed as

Anti-HIV AgentsCoinfectionFemaleHIV InfectionsHumansImmune Reconstitution Inflammatory SyndromeMiddle AgedTuberculosis, PulmonaryAnti-HIV AgentsHIVImmune reconstitution inflammatory syndromeIRISTuberculosis

Identifiers

PMID31208430
PMCPMC6580602

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.