Evidence map›Paper›PMID 31208406›Full record

Observational studyRespiratory research2019

Demographic and clinical profile of idiopathic pulmonary fibrosis patients in Spain: the SEPAR National Registry.

Estrella Fernández-Fabrellas, María Molina-Molina, Joan B Soriano, José Antonio Rodríguez Portal, Julio Ancochea, Claudia Valenzuela, Antoni Xaubet, SEPAR-IPF National Registry

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Respiratory research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

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  6. Aging and lung diseases: Unraveling mechanisms and therapeutic targets.Chinese medical journal pulmonary and critical care medicine · 2025
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  9. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Estrella Fernández-FabrellasPulmonology Department, Consorcio Hospital General Universitario, Valencia, Spain.
María Molina-MolinaInterstitial Diseases Unit, Respiratory Department, Hospital Universitario de Bellvitge, Carrer de la Feixa Llarga, S/N, 08907 - L'Hospitalet de Llobregat, Barcelona, Spain. mariamolinamolina@hotmail.com.ORCID http://orcid.org/0000-0002-1852-1723
Joan B SorianoPulmonology Department, Hospital Universitario de La Princesa, Madrid, Spain.
José Antonio Rodríguez PortalPulmonology Department, Hospital Universitario Virgen del Rocio, Sevilla, Spain.
Julio AncocheaPulmonology Department, Hospital Universitario de La Princesa, Madrid, Spain.
Claudia ValenzuelaPulmonology Department, Hospital Universitario de La Princesa, Madrid, Spain.
Antoni XaubetPulmonology Department, Hospital Clinic, Barcelona, Spain.
SEPAR-IPF National Registry

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known on the characteristics of patients diagnosed with idiopathic pulmonary fibrosis (IPF) in Spain. We aimed to characterize the demographic and clinical profile of IPF patients included in the IPF National Registry of the Spanish Respiratory Society (SEPAR).

methodsThis is a prospective, observational, multicentre and nationwide study that involved 608 IPF patients included in the SEPAR IPF Registry up to June 27th, 2017, and who received any treatment for their disease. IPF patients were predominantly males, ex-smokers, and aged in their 70s, similar to other registries.

resultsUpon inclusion, mean ± SD predicted forced vital capacity was 77.6% ± 19.4, diffusing capacity for carbon monoxide was 48.5% ± 17.7, and the 6-min walk distance was 423.5 m ± 110.4. The diagnosis was mainly established on results from the high-resolution computed tomography in the proper clinical context (55.0% of patients), while 21.2% of patients required invasive procedures (surgical lung biopsy) for definitive diagnosis. Anti-fibrotic treatment was prescribed in 69.4% of cases, 51.5% pirfenidone and 17.9% nintedanib, overall with a good safety profile.

conclusionsThe SEPAR IPF Registry should help to further characterize current characteristics and future trends of IPF patients in Spain and compare/pool them with other registries and cohorts.

Indexed as

RegistriesSocieties, MedicalAgedAged, 80 and overAnti-Inflammatory Agents, Non-SteroidalFemaleHumansIdiopathic Pulmonary FibrosisMaleMiddle AgedProspective StudiesPyridonesRetrospective StudiesSpainAnti-Inflammatory Agents, Non-SteroidalpirfenidonePyridonesAnti-fibrotic treatmentIdiopathic pulmonary fibrosisNational registrySEPARSpain

Identifiers

PMID31208406
PMCPMC6580511

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.