Evidence map›Paper›PMID 31208388›Full record

ArticleBMC pulmonary medicine2019

"Characteristics of patients admitted to emergency department for asthma attack: a real-LIFE study".

Laura Losappio, Enrico Heffler, Rossella Carpentiere, Monica Fornero, Cosimo Damiano Cannito, Francesco Guerrera, Francesca Puggioni, Riccardo Monti, Stefania Nicola, Giovanni Rolla and 1 more

Abstract read
In one paragraph

Article in BMC pulmonary medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  4. Audit of Asthma Exacerbation Management in a Swiss General Hospital.Respiration; international review of thoracic diseases · 2023
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Laura LosappioAllergy and Immunology Department, Niguarda Ca Granda Hospital, Milan, Italy.
Enrico HefflerPersonalized Medicine, Asthma and Allergy, Humanitas Research Hospital, Rozzano, Italy.
Rossella CarpentiereEmergency Department, "Dimiccoli" Hospital, Barletta, Italy.
Monica ForneroAllergy and Immunology Department, Niguarda Ca Granda Hospital, Milan, Italy.
Cosimo Damiano CannitoEmergency Department, "Dimiccoli" Hospital, Barletta, Italy.
Francesco GuerreraDepartment of Surgical Science, University of Torino, Torino, Italy.
Francesca PuggioniPersonalized Medicine, Asthma and Allergy, Humanitas Research Hospital, Rozzano, Italy.
Riccardo MontiAllergy and Clinical Immunology Unit, Department of Medical Science, University of Torino and AO Ordine Mauriziano Umberto I, Torino, Italy.
Stefania NicolaAllergy and Clinical Immunology Unit, Department of Medical Science, University of Torino and AO Ordine Mauriziano Umberto I, Torino, Italy.
Giovanni RollaAllergy and Clinical Immunology Unit, Department of Medical Science, University of Torino and AO Ordine Mauriziano Umberto I, Torino, Italy.
Luisa BrussinoAllergy and Clinical Immunology Unit, Department of Medical Science, University of Torino and AO Ordine Mauriziano Umberto I, Torino, Italy. luisa.brussino@unito.it.ORCID http://orcid.org/0000-0001-7249-7616

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAsthma is a chronic disease affecting 30 million people in Europe under 45y. Poor control of Asthma is the main cause of emergency-department (ED) access, becoming the strongest determinant of the economic burden of asthma management.

objectiveTo examine the characteristics of adult patients admitted to ED for acute asthma attack, focusing on previous diagnosis of asthma (DA) and current therapy.

methodsDuring a one-year period, a structured questionnaire, assessing asthma diagnosis and management, was administered to all patients admitted for asthma attack, to the ED of a South-Italy town. Only patients with subsequently confirmed asthma were enrolled. The data on oxygen saturation (Sat.O2), heart and respiratory-rate, severity code ED-admission, hospitalization or discharge, had been obtained.

resultsTwo hundred one patients (mean 50.3ys), were enrolled. One hundred eighteen had a DA, made 17.5 ± 5.88 years before, and 35.6% had a specialist-examination in the last year. 53.3% of DA-patients used a self-medication before ED access with short-acting-beta-2-agonist and oral-corticosteroids, although none had a written-asthma-action-plan (WAAP). Almost all DA-patients were on regular therapy: inhaled-corticosteroids (ICS) in 61%, associated with LABA in 85%. 16.7% of DA-patients had previous DA-access. The overall hospitalization-rate was 39%, higher in DA compared to unknown asthmatic patients (UA)(p = 0.017). Significant risk factors for hospitalization were Sat-O2 ≤ 94% breathing ambient air (OR9.91, p < 0.001), inability-to-complete a sentence (OR9.42,p < 0.001) and the age (OR1.02,p = 0.049).

conclusionDespite the asthma guidelines-recommendation, up to 40% of patients received the asthma diagnosis in ED, only 61% of DA-patients were taking ICS. It is disappointing that DA-patients did not have a WAAP, which could explain the poor patient-self-medication at ED admission.

Indexed as

Administration, InhalationAdolescentAdrenal Cortex HormonesAdultAnti-Asthmatic AgentsAsthmaChildEmergency Service, HospitalFemaleHumansItalyLogistic ModelsMaleMiddle AgedMultivariate AnalysisNebulizers and VaporizersAdrenal Cortex HormonesAnti-Asthmatic AgentsAdult asthmaAllergic asthmaAnti-asthmatic drugsAsthma attackAsthma therapy

Identifiers

PMID31208388
PMCPMC6580601

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.