ArticleBMC evolutionary biology2019
A genome-wide scan for genes under balancing selection in the plant pathogen Ralstonia solanacearum.
Article in BMC evolutionary biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- A century of anthropogenic perturbations impact genomic signatures of the iconic migratory Atlantic cod.Science advances · 2025Article
- The transcription regulator ChpA affects the global transcriptome including quorum sensing-dependent genes in Ralstonia pseudosolanacearum strain OE1-1.Molecular plant pathology · 2023Article
- Article
- Balancing selection on an MYB transcription factor maintains the twig trichome color variation in Melastoma normale.BMC biology · 2023Article
- Global diversity and distribution of prophages are lineage-specific within the Ralstonia solanacearum species complex.BMC genomics · 2022Article
- Honey Bee Habitat Sharing Enhances Gene Flow of the Parasite Nosema ceranae.Microbial ecology · 2022Article
- Stabilizing selection on Atlantic cod supergenes through a millennium of extensive exploitation.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- PhcQ mainly contributes to the regulation of quorum sensing-dependent genes, in which PhcR is partially involved, in Ralstonia pseudosolanacearum strain OE1-1.Molecular plant pathology · 2021Article
- Essential Amino Acid Enrichment and Positive Selection Highlight Endosymbiont's Role in a Global Virus-Vectoring Pest.mSystems · 2021Article
- Host-parasite co-evolution and its genomic signature.Nature reviews. Genetics · 2020Review
- Diversity and evolutionary dynamics of spore-coat proteins in spore-forming species of Bacillales.Microbial genomics · 2020Article
- Taxonomy and Phylogenetic Research on Ralstonia solanacearum Species Complex: A Complex Pathogen with Extraordinary Economic Consequences.Pathogens (Basel, Switzerland) · 2020Review
- Diversity and Evolutionary Dynamics of Antiphage Defense Systems inFrontiers in microbiology · 2020Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlant pathogens are under significant selective pressure by the plant host. Consequently, they are expected to have adapted to this condition or contribute to evading plant defenses. In order to acquire long-term fitness, plant bacterial pathogens are usually forced to maintain advantageous genetic diversity in populations. This strategy ensures that different alleles in the pathogen's gene pool are maintained in a population at frequencies larger than expected under neutral evolution. This selective process, known as balancing selection, is the subject of this work in the context of a common bacterial phytopathogen. We performed a genome-wide scan of Ralstonia solanacearum species complex, an aggressive plant bacterial pathogen that shows broad host range and causes a devastating disease called 'bacterial wilt'.
resultsUsing a sliding window approach, we analyzed 57 genomes from three phylotypes of the R. solanacearum species complex to detect signatures of balancing selection. A total of 161 windows showed extreme values in three summary statistics of population genetics: Tajima's D, θ
conclusionsWe identified various genes under balancing selection that play a significant role in basic metabolism as well as in virulence of the R. solanacearum species complex. These genes are useful to understand and monitor the evolution of bacterial pathogen populations and emerge as potential candidates for future treatments to induce specific plant immune responses.
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