Evidence map›Paper›PMID 31208278›Full record

ArticleCell cycle (Georgetown, Tex.)2019

LncRNA XIST facilitates cell growth, migration and invasion via modulating H3 histone methylation of DKK1 in neuroblastoma.

Jiao Zhang, Wen-Ya Li, Yang Yang, Li-Zhao Yan, Song-Yang Zhang, Jing He, Jia-Xiang Wang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. LncRNA-Mediated Adipogenesis in Different Adipocytes.International journal of molecular sciences · 2022
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Drug Discovery of DKK1 Inhibitors.Frontiers in pharmacology · 2022
    Review
  13. Review
  14. Long non-coding RNA XIST: a novel oncogene in multiple cancers.Molecular medicine (Cambridge, Mass.) · 2021
    Review
  15. Pyroptosis: mechanisms and diseases.Signal transduction and targeted therapy · 2021
    Review
  16. Review
  17. Biological Function of Long Non-coding RNA (LncRNA) Xist.Frontiers in cell and developmental biology · 2021
    Review
  18. Emerging Roles of LncRNAs in the EZH2-regulated Oncogenic Network.International journal of biological sciences · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jiao Zhanga Department of Pediatric Surgery, the First Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Wen-Ya Lia Department of Pediatric Surgery, the First Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Yang Yanga Department of Pediatric Surgery, the First Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Li-Zhao Yana Department of Pediatric Surgery, the First Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Song-Yang Zhanga Department of Pediatric Surgery, the First Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
Jing Heb Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University , Guangzhou , Guangdong , China.
Jia-Xiang Wanga Department of Pediatric Surgery, the First Affiliated Hospital of Zhengzhou University , Zhengzhou , Henan , China.
First Affiliated Hospital of Zhengzhou University · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) have been confirmed to be aberrantly expressed and involved in the progression of neuroblastoma. This study aimed to explore the expression profile of lncRNA X-inactive specific transcript (XIST) and its functional involvement in neuroblastoma. In this study, the relative level of XIST in neuroblastoma tissues and cell lines was detected by qPCR, and DKK1 protein expression was determined using western blot. The effect of XIST on cell growth, invasion and migration

Indexed as

AnimalsCell Line, TumorCell MovementCell ProliferationDown-RegulationEnhancer of Zeste Homolog 2 ProteinGene Expression Regulation, NeoplasticHEK293 CellsHeterograftsHistonesHumansIntercellular Signaling Peptides and ProteinsMaleMethylationMiceMice, Inbred BALB CDKK1 protein, humanEnhancer of Zeste Homolog 2 ProteinEZH2 protein, humanHistonesIntercellular Signaling Peptides and ProteinsRNA, Long NoncodingXIST non-coding RNADKK1EZH2histone methylationNeuroblastomaXIST

Identifiers

PMID31208278
PMCPMC6681787
OpenAlexW2949927632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.