ArticleAsian-Australasian journal of animal sciences2020
Effect of zinc addition on the immune response and production performance of broilers: a meta-analysis.
Article in Asian-Australasian journal of animal sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Effects of vitamin E supplementation on sow gestation: a meta-analysis.Open veterinary journal · 2025Pooled it
- A Meta-analysis of Responses of Broiler Chickens to Dietary Zinc Supplementation: Feed Intake, Feed Conversion Ratio and Average Daily Gain.Biological trace element research · 2023Pooled it
- The effects of lactic acid bacteria and yeasts as probiotics on the growth performance, relative organ weight, blood parameters, and immune responses of broiler: A meta-analysis.F1000Research · 2021Pooled it
- The Relationship Between Blood Urea Nitrogen to Albumin Ratio (BAR) and Diabetic Foot Ulcer (DFU) in Diabetic Patients.Healthcare (Basel, Switzerland) · 2026Article
- Amino Acid Complexed Minerals Zn, Mn, and Cu Improve Bone and Intestinal Characteristics in Laying Pullets.Biological trace element research · 2026Article
- Growth performance and bone zinc concentration in broiler chickens with dietary supplementation of organic zinc.Animal bioscience · 2026Article
- Synergistic effects of zinc oxide and selenium nanoparticles in drinking water on broiler chicken growth, antioxidant, and immunity responses.Veterinary and animal science · 2025Article
- Effects of Zinc Amino Acid Complex Supplementation on Welfare, Carcass Traits, Tibia Health, Meat Quality and Myopathies in Broilers.Veterinary medicine and science · 2025Article
- Impact of dietary zinc nanoparticles and probiotics on broiler health and productivity.Journal of advanced veterinary and animal research · 2025Article
- Modulating effects ofFrontiers in microbiology · 2025Article
- Synergistic impact of Chlorella vulgaris, zinc oxide- and/or selenium nanoparticles dietary supplementation on broiler's growth performance, antioxidant and blood biochemistry.Tropical animal health and production · 2024Article
- Optimization of solvent and extraction time on secondary metabolite content of mangosteen leaf (Journal of advanced veterinary and animal research · 2024Article
- Evaluating the effect of optimal zinc amino-acid complex supplementation in laying pullets on performance and zinc retention.PloS one · 2024Article
- Supplementation of Zinc on Antioxidant Activity, Blood Profile, Mineral Availability, Abdominal Fat, Digestive and Accessory Organs of Sikumbang Janti Duck.Archives of Razi Institute · 2023Article
- Effect of combined in ovo administration of zinc glycine chelate (Zn-Gly) and a multistrain probiotic on the modulation of cellular and humoral immune responses in broiler chickens.Poultry science · 2023Article
- Serum inflammation and oxidative DNA damage amelioration in cocks-fed supplementalTranslational animal science · 2023Article
- Effect of stocking density and vitamin E or zinc supplementation on growth, physiology, gene expression, and economic efficiency of growing broiler chicks.Tropical animal health and production · 2022Article
- Effect of dietary supplementation of zinc proteinate on performance, egg quality, blood biochemical parameters, and egg zinc content in White Leghorn layers.Tropical animal health and production · 2022Article
- Effect of vitamin E supplementation on chicken sperm quality: A meta-analysis.Veterinary world · 2022Article
- Essential oils as growth-promoting additives on performance, nutrient digestibility, cecal microbes, and serum metabolites of broiler chickens: a meta-analysis.Animal bioscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study performed a meta-analysis of published trials to determine the effects of zinc addition on the immune response and production performance of broilers.
methodsA database was built from published literature regarding the addition of zinc forms or doses and their relation to the immune response and production performance of broilers. Different doses or forms of zinc were identified in the database. The recorded parameters were related to the immune response and production performance. The database contained a total of 323 data points from 41 studies that met the criteria. Then, the data were processed for a meta-analysis using a mixed model methodology. The doses or different forms of zinc were considered fixed effects, different studies were treated as random effects, and P-values were used as the model statistics.
resultsAn increase in zinc dose increased (p<0.05) pancreas metallothionein (MT) and zinc concentrations in the plasma, tibia and meat, all in quadratic patterns, but linearly decreased (p<0.05) the heterophil/lymphocyte (H/L) ratio. With regard to the different zinc forms, both inorganic and organic zinc increased (p<0.05) the zinc concentrations in the plasma and tibia, the calcium and phosphorus contents in the tibia, and the antioxidant activity of superoxide dismutase (SOD) in meat as compared to control. An increase in zinc dose increased average daily gain (ADG) and decreased feed conversion ratio (FCR) by following a quadratic pattern (p<0.05). Inorganic and organic zinc decreased (p<0.05) FCR and H/L ratio than that of control, but these two forms were similar for these parameters.
conclusionZinc addition has a positive impact on immunity and broiler production. Zinc can suppress stress and inhibit the occurrence of lipid peroxidation in broilers, and it can also improve ADG, FCR and the quality of broiler carcasses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.