Evidence map›Paper›PMID 31208154›Full record

ArticleGenes2019

Ankrd45 Is a Novel Ankyrin Repeat Protein Required for Cell Proliferation.

Yunsi Kang, Haibo Xie, Chengtian Zhao

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yunsi KangInstitute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China. kangyunsi@stu.ouc.edu.cn.
Haibo XieInstitute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China. xiehaibo@stu.ouc.edu.cn.
Chengtian ZhaoInstitute of Evolution & Marine Biodiversity, Ocean University of China, Qingdao 266003, China. chengtian_zhao@ouc.edu.cn.
Ocean University of China · CNQingdao National Laboratory for Marine Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ankyrin repeats, the most common protein-protein interaction motifs in nature, are widely present in proteins of both eukaryotic and prokaryotic cells. Ankyrin repeat-containing proteins play diverse biological functions. Here, we identified the gene ankrd45, which encodes a novel, two ankyrin repeat-containing protein. Zebrafish ankrd45 displayed a tissue specific expression pattern during early development, with high expression in ciliated tissues, including otic vesicles, Kupffer's vesicles, pronephric ducts, and floor plates. Surprisingly, zebrafish ankrd45 mutants were viable and developed grossly normal cilia. In contrast, mutant larvae developed enlarged livers when induced with liver specific expression of Kras

Indexed as

AnimalsAnkyrin RepeatBody PatterningCell ProliferationCiliaCRISPR-Cas SystemsEmbryonic DevelopmentGene Expression Regulation, DevelopmentalHeLa CellsHumansLarvaMitosisZebrafishZebrafish ProteinsZebrafish ProteinsANKRD45apoptosiscancercell cycleKRASzebrafish

Identifiers

PMID31208154
PMCPMC6628321
OpenAlexW2951469247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.