Evidence map›Paper›PMID 31208093›Full record

ArticleJournal of clinical medicine2019

Effects of a High Fat Meal Associated with Water, Juice, or Champagne Consumption on Endothelial Function and Markers of Oxidative Stress and Inflammation in Young, Healthy Subjects.

Olivier Rouyer, Cyril Auger, Anne-Laure Charles, Samy Talha, Alain Meyer, Francois Piquard, Emmanuel Andres, Valerie Schini-Kerth, Bernard Geny

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Mechanisms of Atherosclerosis Induced by Postprandial Lipemia.Frontiers in cardiovascular medicine · 2021
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Olivier RouyerUniversité de Strasbourg, Fédération de médecine translationnelle de Strasbourg (FMTS), Faculté de Médecine, Equipe d'accueil 3072, 11 Rue Humann, 67000 Strasbourg, France. Olivier.rouyer@chru-strasbourg.fr.
Cyril AugerCNRS UMR 7213, Laboratoire de Biophotonique et Pharmacologie, Faculté de Pharmacie, Université de Strasbourg, 67401 Illkirch, France. cyril.auger@unistra.fr.
Anne-Laure CharlesUniversité de Strasbourg, Fédération de médecine translationnelle de Strasbourg (FMTS), Faculté de Médecine, Equipe d'accueil 3072, 11 Rue Humann, 67000 Strasbourg, France. anne.laure.charles@unistra.fr.
Samy TalhaUniversité de Strasbourg, Fédération de médecine translationnelle de Strasbourg (FMTS), Faculté de Médecine, Equipe d'accueil 3072, 11 Rue Humann, 67000 Strasbourg, France. samy.talha@chru-strasbourg.fr.
Alain MeyerUniversité de Strasbourg, Fédération de médecine translationnelle de Strasbourg (FMTS), Faculté de Médecine, Equipe d'accueil 3072, 11 Rue Humann, 67000 Strasbourg, France. alain.meyer1@chru-strasbourg.fr.
Francois PiquardUniversité de Strasbourg, Fédération de médecine translationnelle de Strasbourg (FMTS), Faculté de Médecine, Equipe d'accueil 3072, 11 Rue Humann, 67000 Strasbourg, France. francois.piquard@wanadoo.fr.
Emmanuel Andres.Service de Médecine Interne, Diabète et Maladies Métaboliques, Pôle M.I.R.N.E.D., Hôpitaux Universitaires, CHRU Strasbourg, 67000 Cedex, France. Emmanuel.andres@chru-strasbourg.fr.
Valerie Schini-KerthCNRS UMR 7213, Laboratoire de Biophotonique et Pharmacologie, Faculté de Pharmacie, Université de Strasbourg, 67401 Illkirch, France. valerie.schini-kerth@pharma.u-strasbg.fr.
Bernard GenyUniversité de Strasbourg, Fédération de médecine translationnelle de Strasbourg (FMTS), Faculté de Médecine, Equipe d'accueil 3072, 11 Rue Humann, 67000 Strasbourg, France. bernard.geny@chru-strasbourg.fr.
Hôpitaux Universitaires de Strasbourg · FRCentre National de la Recherche Scientifique · FRUniversité de Strasbourg · FR

Funding

Strasbourg's clinical research directory of the University Hospital, by the Comité Interprofessionnel du Vin de Champagne (C.I.V.C.) and by Granini GmBh. 0
6 · The paper itself

Abstract

Endothelial dysfunction (ED), often linked to hypertriglyceridemia, is an early step of atherosclerosis. We investigated, in a randomized cross-over study, whether high-fat meal (HFM)-induced ED might be reduced by fruit juice or champagne containing polyphenols. Flow-mediated dilatation (FMD) and biological parameters (lipid profile, glycemia, inflammation, and oxidative stress markers) were determined before and two and three hours after the HFM in 17 healthy young subjects (24.6 ± 0.9 years) drinking water, juice, or champagne. Considering the entire group, despite significant hypertriglyceridemia (from 0.77 ± 0.07 to 1.41 ± 0.18 mmol/L,

Indexed as

champagneendothelial functionflow-mediated dilatationglycemiahigh-fat mealhypertriglyceridemiainflammationjuiceoxidative stresspolyphenols

Identifiers

PMID31208093
PMCPMC6617404
OpenAlexW2951484796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.