Evidence map›Paper›PMID 31208085›Full record

ArticlePharmaceutics2019

Photodynamic Therapy of Ovarian Carcinoma Cells with Curcumin-Loaded Biodegradable Polymeric Nanoparticles.

Lili Duse, Michael Rene Agel, Shashank Reddy Pinnapireddy, Jens Schäfer, Mohammed A Selo, Carsten Ehrhardt, Udo Bakowsky

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 92 citations in OpenAlex.

  1. Review
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  6. Study on Recovery Strategy of Hearing Loss & SGN Regeneration Under Physical Regulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  7. Article
  8. Review
  9. Nanotechnology for the Diagnosis and Treatment of Liver Cancer.International journal of nanomedicine · 2024
    Review
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Lili DuseDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Str. 4, 35037 Marburg, Germany. lili.duse@pharmazie.uni-marburg.de.
Michael Rene AgelDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Str. 4, 35037 Marburg, Germany. michael.agel@pharmazie.uni-marburg.de.
Shashank Reddy PinnapireddyDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Str. 4, 35037 Marburg, Germany. shashank.pinnapireddy@pharmazie.uni-marburg.de.ORCID 0000-0003-4036-7619
Jens SchäferDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Str. 4, 35037 Marburg, Germany. j.schaefer@staff.uni-marburg.de.
Mohammed A SeloSchool of Pharmacy and Pharmaceutical Sciences and Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland. mohammeda.mohsin@uokufa.edu.iq.ORCID 0000-0002-6814-4575
Carsten EhrhardtSchool of Pharmacy and Pharmaceutical Sciences and Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland. ehrhardc@tcd.ie.ORCID 0000-0003-0730-1829
Udo BakowskyDepartment of Pharmaceutics and Biopharmaceutics, University of Marburg, Robert-Koch-Str. 4, 35037 Marburg, Germany. ubakowsky@aol.com.
Philipps University of Marburg · DETrinity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulation of photosensitisers in photodynamic therapy in healthy tissues is often the cause of unwanted side effects. Using nanoparticles, improved bioavailability and site-specific drug uptake can be achieved. In this study, curcumin, a natural product with anticancer properties, albeit with poor aqueous solubility, was encapsulated in biodegradable polymeric poly(lactic-

Indexed as

cancercellular uptakeLEDnanoscaled drug deliveryPLGAreactive oxygen speciesserum stability

Identifiers

PMID31208085
PMCPMC6630253
OpenAlexW2950233799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.