Evidence map›Paper›PMID 31208028›Full record

ArticleGenes2019

Full-Length Hairpin RNA Accumulates at High Levels in Yeast but Not in Bacteria and Plants.

Chengcheng Zhong, Neil A Smith, Daai Zhang, Simon Goodfellow, Ren Zhang, Weixing Shan, Ming-Bo Wang

Open access · goldAbstract read
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Harnessing double-stranded RNA (dsRNA): a sustainable approach to pest management.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  4. Regulation of Plant Genes with Exogenous RNAs.International journal of molecular sciences · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Chengcheng ZhongState Key Laboratory of Crop Stress Biology for Arid Areas, Northwest A&F University, Yangling 712100, China. zcc_1127@hotmail.com.ORCID 0000-0001-7613-111X
Neil A SmithCommonwealth Scientific and Industrial Research Organisation (CSIRO) Agriculture and Food, Canberra, ACT 2601, Australia. neil.smith@csiro.au.
Daai ZhangCommonwealth Scientific and Industrial Research Organisation (CSIRO) Agriculture and Food, Canberra, ACT 2601, Australia. anna.zhang@csiro.au.
Simon GoodfellowSchool of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia. sg389@uowmail.edu.au.
Ren ZhangSchool of Chemistry and Molecular Bioscience, University of Wollongong, NSW 2522, Australia. rzhang@uow.edu.au.
Weixing ShanState Key Laboratory of Crop Stress Biology for Arid Areas, Northwest A&F University, Yangling 712100, China. wxshan@nwafu.edu.cn.
Ming-Bo WangCommonwealth Scientific and Industrial Research Organisation (CSIRO) Agriculture and Food, Canberra, ACT 2601, Australia. ming-bo.wang@csiro.au.
Commonwealth Scientific and Industrial Research Organisation · AUUniversity of Wollongong · AUNorthwest A&F University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hairpin-structured (hp) RNA has been widely used to induce RNA interference (RNAi) in plants and animals, and an in vivo expression system for hpRNA is important for large-scale RNAi applications. Bacterial expression systems have so far been developed for in vivo expression of hpRNA or double-stranded (ds) RNA, but the structure of the resulting RNAi molecules has remained unclear. Here we report that long hpRNAs expressed in the bacteria

Indexed as

Nucleic Acid ConformationAgrobacteriumEscherichia coliLoss of Function MutationNicotianaPlants, Genetically ModifiedRibonuclease IIIRNA, Double-StrandedRNA InterferenceSaccharomyces cerevisiaeRibonuclease IIIRNA, Double-Strandeddouble-stranded RNAhairpin RNARNA interferenceyeast

Identifiers

PMID31208028
PMCPMC6627737
OpenAlexW2950616871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.