Evidence map›Paper›PMID 31207979›Full record

ArticleGenes2019

A Novel Role for Polycystin-2 (Pkd2) in

Megan S Valentine, Junji Yano, Judith Van Houten

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Teaching molecular genetics usingJournal of microbiology & biology education · 2025
    Article
  2. Frontiers in cell and developmental biology · 2022
    Review
  3. UsingGenes · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Megan S ValentineState University of New York at Plattsburgh, 101 Broad Street, Plattsburgh, NY 12901, USA. mvale016@plattsburgh.edu.
Junji YanoUniversity of Vermont, Department of Biology, 120 Marsh Life Science, 109 Carrigan Drive, Burlington, VT 05405, USA. junji.yano@uvm.edu.
Judith Van HoutenUniversity of Vermont, Department of Biology, 120 Marsh Life Science, 109 Carrigan Drive, Burlington, VT 05405, USA. Judith.Vanhouten@uvm.edu.
University of Vermont · USSUNY Plattsburgh · US

Funding

Vermont INBRE Administrative Supplement 2024 AWD 118P20GM103449 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI CHRISTOPHER S FRANCKLYN · 2012 to 2026
$58.4M
Center for Neuroscience ExcellenceP30GM103498 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PARSONS, RODNEY L · 2012 to 2015
$4.3M
CENTER FOR NEUROSCIENCE EXCELLENCEP30RR032135 · NCRR · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI PARSONS, RODNEY L · 2011 to 2011
$1.1M
NCRR NIH HHS P30 RR032135NIGMS NIH HHS P20 GM103449NIGMS NIH HHS P30 GM103498
6 · The paper itself

Abstract

A human ciliopathy gene codes for Polycystin-2 (Pkd2), a non-selective cation channel. Here, the Pkd2 channel was explored in the ciliate

Indexed as

CalciumCell MembraneCell Membrane PermeabilityCiliaGene Expression RegulationHumansMagnesiumMutationOligopeptidesParamecium tetraureliaTRPP Cation ChannelsCalciumFLAG peptideMagnesiumOligopeptidesTRPP Cation Channelsbehaviorcell body membranechannelopathyciliaelectrophysiologymagnesium channelover-expressionPolycystin-2trafficking

Identifiers

PMID31207979
PMCPMC6627415
OpenAlexW2949876100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.