Evidence map›Paper›PMID 31207930›Full record

ReviewCancers2019

Optimizing Neuro-Oncology Imaging: A Review of Deep Learning Approaches for Glioma Imaging.

Madeleine M Shaver, Paul A Kohanteb, Catherine Chiou, Michelle D Bardis, Chanon Chantaduly, Daniela Bota, Christopher G Filippi, Brent Weinberg, Jack Grinband, Daniel S Chow and 1 more

Abstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Trial
  2. Improving Pre-trained Adult Glioma Segmentation Models using only Post-processing Techniques.Segmentation, classification, and synthesis for brain tumors and traumatic brain injuries : MICCAI 2025 Challenges: BraTS-Lighthouse 2025 and AIMS-TBI 2025, held in conjunction with MICCAI 2025, Daejeon, South Korea, September 23, 2025,... · 2026
    Article
  3. Review
  4. Review
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  8. Article
  9. Dual Deep CNN for Tumor Brain Classification.Diagnostics (Basel, Switzerland) · 2023
    Article
  10. Review
  11. Article
  12. Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Madeleine M ShaverDepartment of Radiology, University of California, Irvine, Orange, CA 92868-3201, USA. mshaver@uci.edu.
Paul A KohantebDepartment of Radiology, University of California, Irvine, Orange, CA 92868-3201, USA. pkohante@uci.edu.
Catherine ChiouDepartment of Radiology, University of California, Irvine, Orange, CA 92868-3201, USA. clchiou@uci.edu.
Michelle D BardisDepartment of Radiology, University of California, Irvine, Orange, CA 92868-3201, USA. mbardis@uci.edu.ORCID 0000-0002-3223-2127
Chanon ChantadulyDepartment of Radiology, University of California, Irvine, Orange, CA 92868-3201, USA. cchantad@uci.edu.
Daniela BotaDepartment of Neurology, University of California, Irvine, Orange, CA 92868-3201, USA. dbota@uci.edu.
Christopher G FilippiDepartment of Radiology, North Shore University Hospital, Manhasset, NY 11030, USA. sairaallapeikko@gmail.com.
Brent WeinbergDepartment of Radiology, Emory University School of Medicine, Atlanta, GA 30322, USA. Brent.d.weinberg@gmail.com.ORCID 0000-0002-7992-1747
Jack GrinbandDepartment of Radiology, Columbia University, New York, NY 10032, USA. jackgrinband@gmail.com.ORCID 0000-0001-7658-6755
Daniel S ChowDepartment of Radiology, University of California, Irvine, Orange, CA 92868-3201, USA. chowd3@uci.edu.
Peter D ChangDepartment of Radiology, University of California, Irvine, Orange, CA 92868-3201, USA. changp6@uci.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiographic assessment with magnetic resonance imaging (MRI) is widely used to characterize gliomas, which represent 80% of all primary malignant brain tumors. Unfortunately, glioma biology is marked by heterogeneous angiogenesis, cellular proliferation, cellular invasion, and apoptosis. This translates into varying degrees of enhancement, edema, and necrosis, making reliable imaging assessment challenging. Deep learning, a subset of machine learning artificial intelligence, has gained traction as a method, which has seen effective employment in solving image-based problems, including those in medical imaging. This review seeks to summarize current deep learning applications used in the field of glioma detection and outcome prediction and will focus on (1) pre- and post-operative tumor segmentation, (2) genetic characterization of tissue, and (3) prognostication. We demonstrate that deep learning methods of segmenting, characterizing, grading, and predicting survival in gliomas are promising opportunities that may enhance both research and clinical activities.

Indexed as

artificial intelligencedeep learningglioblastomagliomamachine learningneural network

Identifiers

PMID31207930
PMCPMC6627902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.