Evidence map›Paper›PMID 31207929›Full record

ArticleNutrients2019

Attenuation of UVB-Induced Photo-Aging by Polyphenolic-Rich Spatholobus Suberectus Stem Extract Via Modulation of MAPK/AP-1/MMPs Signaling in Human Keratinocytes.

Kyoo-Ri Kwon, Md Badrul Alam, Ji-Hyun Park, Tae-Ho Kim, Sang-Han Lee

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 150 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Protective Effects ofInternational journal of molecular sciences · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Role, mechanisms and effects ofOncology letters · 2025
    Review
  16. Article
  17. Exploring Anti-Aging Potential ofNanotechnology, science and applications · 2025
    Article
  18. Article
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kyoo-Ri KwonDepartment of Food Science & Biotechnology, Kyungpook National University, Daegu 41566, Korea. rbfl0116@knu.ac.kr.
Md Badrul AlamDepartment of Food Science & Biotechnology, Kyungpook National University, Daegu 41566, Korea. mbalam@knu.ac.kr.ORCID 0000-0002-8509-6827
Ji-Hyun ParkDepartment of Food Science & Biotechnology, Kyungpook National University, Daegu 41566, Korea. wlgus6744@knu.ac.kr.
Tae-Ho KimBiomedical Research Institute, Kyungpook National University Hospital, Daegu 41944, Korea. kimth0929@ynu.ac.kr.
Sang-Han LeeDepartment of Food Science & Biotechnology, Kyungpook National University, Daegu 41566, Korea. sang@knu.ac.kr.ORCID 0000-0002-2343-7315
Kyungpook National University · KRKyungpook National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is well known that ultraviolet light activates mitogen-activated protein (MAP) kinase by increasing the reactive oxygen species (ROS) in the body, enhancing activating protein 1(AP-1) complexes (c-Jun and c-Fos), increasing matrix metalloproteinases (MMPs) and degrading collagen and elastin. In this study, we confirmed that polyphenolic rich

Indexed as

Cell LineCollagen Type I, alpha 1 ChainFabaceaeHumansKeratinocytesMAP Kinase Signaling SystemMatrix MetalloproteinasesPlant ExtractsPlant StemsPolyphenolsSkin AgingTranscription Factor AP-1Ultraviolet RaysCOL1A1 protein, humanCollagen Type I, alpha 1 ChainMatrix MetalloproteinasesPlant ExtractsPolyphenolsTranscription Factor AP-1anti-agingcollagen type I alpha 1 (COL1A1)elastin (ELN)matrix metalloproteinases (MMPs)mitogen-activated protein kinase (MAPK)Spatholobus suberectus

Identifiers

PMID31207929
PMCPMC6627339
OpenAlexW2951872997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.